Sharon M. Shepherd

GlcNAcstatin:  a Picomolar, Selective <i>O</i>-GlcNAcase Inhibitor That Modulates Intracellular <i>O</i>-GlcNAcylation Levels

Helge C. Dorfmueller, Vladimir S. Borodkin, Marianne Schimpl et al. · Journal of the American Chemical Society · 2006 · 143 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

Lysyl-tRNA synthetase as a drug target in malaria and cryptosporidiosis

Beatriz Baragaña, Barbara Forte, Ryan Choi et al. · Proceedings of the National Academy of Sciences · 2019 · 139 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Structural insights into mechanism and specificity of O‐GlcNAc transferase

Andrew Clarke, Ramón Hurtado‐Guerrero, Shalini Pathak et al. · The EMBO Journal · 2008 · 119 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +14

Crystal Structures of Penicillin-Binding Protein 3 from Pseudomonas aeruginosa: Comparison of Native and Antibiotic-Bound Forms

Sarah Sainsbury, Louise E. Bird, Vincenzo A. Rao et al. · Journal of Molecular Biology · 2010 · 96 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +13

Chemogenomics identifies acetyl-coenzyme A synthetase as a target for malaria treatment and prevention

Robert L. Summers, Charisse Flerida A. Pasaje, João Pedro Pisco et al. · Cell chemical biology · 2021 · 81 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +16