Hiroto Fujita

Efficacy of Base-Modification on Target Binding of Small Molecule DNA Aptamers

Yuri Imaizumi, Yuuya Kasahara, Hiroto Fujita et al. · Journal of the American Chemical Society · 2013 · 98 citations

Pharmacy, Biotechnology, Molecular Biology +13

Capillary Electrophoresis–Systematic Evolution of Ligands by Exponential Enrichment Selection of Base- and Sugar-Modified DNA Aptamers: Target Binding Dominated by 2′-<i>O</i>,4′-<i>C</i>-Methylene-Bridged/Locked Nucleic Acid Primer

Yuuya Kasahara, Yuuta Irisawa, Hiroto Fujita et al. · Analytical Chemistry · 2013 · 65 citations

Pharmacy, Biochemistry, Molecular Biology +17

Minimal Thioflavin T Modifications Improve Visual Discrimination of Guanine-Quadruplex Topologies and Alter Compound-Induced Topological Structures

Yuka Kataoka, Hiroto Fujita, Yuuya Kasahara et al. · Analytical Chemistry · 2014 · 57 citations

Pharmacy, Biophysics, Molecular Biology +17

Selection, Characterization and Application of Artificial DNA Aptamer Containing Appended Bases with Sub-nanomolar Affinity for a Salivary Biomarker

Hirotaka Minagawa, Kentaro Onodera, Hiroto Fujita et al. · Scientific Reports · 2017 · 57 citations · Full text

Medicine, Chemical Biology, Molecular Biology +15

Novel One-Tube-One-Step Real-Time Methodology for Rapid Transcriptomic Biomarker Detection: Signal Amplification by Ternary Initiation Complexes

Hiroto Fujita, Yuka Kataoka, Seiji Tobita et al. · Analytical Chemistry · 2016 · 39 citations

Life Sciences, Biotechnology, Molecular Biology +14