Karim Iskander

Disruption of Dihydronicotinamide Riboside:Quinone Oxidoreductase 2 (NQO2) Leads to Myeloid Hyperplasia of Bone Marrow and Decreased Sensitivity to Menadione Toxicity

Delwin J. Long, Karim Iskander, Amos Gaikwad et al. · Journal of Biological Chemistry · 2002 · 110 citations · Full text

Life Sciences, Genetics, Molecular Biology +9

NRH:Quinone Oxidoreductase 2 and NAD(P)H:Quinone Oxidoreductase 1 Protect Tumor Suppressor p53 against 20S Proteasomal Degradation Leading to Stabilization and Activation of p53

Xing Gong, Labanyamoy Kole, Karim Iskander et al. · Cancer Research · 2007 · 109 citations · Full text

Life Sciences, Cell Biology, Oncology +16

Lower Induction of p53 and Decreased Apoptosis in <i>NQO1</i>-Null Mice Lead to Increased Sensitivity to Chemical-Induced Skin Carcinogenesis

Karim Iskander, Amos Gaikwad, Marilène Paquet et al. · Cancer Research · 2005 · 80 citations

Medicine, Cancer Biology, Oncology +17

NQO1 and NQO2 Regulation of Humoral Immunity and Autoimmunity

Karim Iskander, Jessica Li, Shuhua Han et al. · Journal of Biological Chemistry · 2006 · 76 citations · Full text

Life Sciences, Immunology, Pathology +15

Deficiency of NRH:Quinone Oxidoreductase 2 Increases Susceptibility to 7,12-Dimethylbenz( <b> <i>a</i> </b> )anthracene and Benzo( <b> <i>a</i> </b> )pyrene-Induced Skin Carcinogenesis

Karim Iskander, Marilène Paquet, Cory Brayton et al. · Cancer Research · 2004 · 62 citations

Medicine, Oncology, Toxicology +15