M H Holguin

Isolation and characterization of a membrane protein from normal human erythrocytes that inhibits reactive lysis of the erythrocytes of paroxysmal nocturnal hemoglobinuria.

M H Holguin, L R Fredrick, Nicole J. Bernshaw et al. · Journal of Clinical Investigation · 1989 · 406 citations · Full text

Immunology, Redox Biology, Bioanalysis +19

Relationship between the membrane inhibitor of reactive lysis and the erythrocyte phenotypes of paroxysmal nocturnal hemoglobinuria.

M H Holguin, LA Wilcox, Nicole J. Bernshaw et al. · Journal of Clinical Investigation · 1989 · 151 citations · Full text

Immunology, Blood Cell, Reactive Lysis +22

Alterations in the topoisomerase II alpha gene, messenger RNA, and subcellular protein distribution as well as reduced expression of the DNA topoisomerase II beta enzyme in a mitoxantrone-resistant HL-60 human leukemia cell line.

W G Harker, David Slade, Rebecca Parr et al. · PubMed · 1995 · 95 citations

Hematological Malignancy, Chromatin, Topo Ii Alpha +15

Analysis of the effects of activation of the alternative pathway of complement on erythrocytes with an isolated deficiency of decay accelerating factor

M H Holguin, Carla Martin, Nicole J. Bernshaw et al. · The Journal of Immunology · 1992 · 65 citations

Selective use of an alternative stop codon and polyadenylation signal within intron sequences leads to a truncated topoisomerase II alpha messenger RNA and protein in human HL-60 leukemia cells selected for resistance to mitoxantrone.

W G Harker, David Slade, Rebecca Parr et al. · PubMed · 1995 · 52 citations

Hematological Malignancy, Chromatin, Radiation Oncology +15