A Bursen

The leukemogenic AF4–MLL fusion protein causes P-TEFb kinase activation and altered epigenetic signatures

A Benedikt, S Baltruschat, Bastian Scholz et al. · Leukemia · 2010 · 85 citations

Chromatin, Medicine, Mixed-phenotype Acute Leukemia +9

Combined effects of the two reciprocal t(4;11) fusion proteins MLL·AF4 and AF4·MLL confer resistance to apoptosis, cell cycling capacity and growth transformation

Till Wenger, Irina Eberle, A Bursen et al. · Oncogene · 2006 · 54 citations

Cell Division, Reciprocal T, Apoptosis +9

Transcription linked to recombination: a gene-internal promoter coincides with the recombination hot spot II of the human MLL gene

Susanne Scharf, Juergen Zech, A Bursen et al. · Oncogene · 2006 · 53 citations

Chromatin, Transcriptional Regulation, Gene-internal Promoter Coincides +10

Activated <i>KRAS</i> Cooperates with MLL-AF4 to Promote Extramedullary Engraftment and Migration of Cord Blood CD34+ HSPC But Is Insufficient to Initiate Leukemia

Cristina Prieto, Ronald W. Stam, Antonio Agraz-Doblás et al. · Cancer Research · 2016 · 40 citations

Kras Activation Cooperates, Mixed-phenotype Acute Leukemia, Immunology +19

Ligand-independent FLT3 activation does not cooperate with MLL-AF4 to immortalize/transform cord blood CD34+ cells

Rosa Montes, Verónica Ayllón, Cristina Prieto et al. · Leukemia · 2013 · 28 citations · Full text

Ligand-independent Flt3 Activation, Cell Interaction, Immunology +5