K Nakano

Antitumor activity of 1 M tegafur-0.4 M 5-chloro-2,4-dihydroxypyridine-1 M potassium oxonate (S-1) against human colon carcinoma orthotopically implanted into nude rats.

Tetsuhiko Shirasaka, K Nakano, T Takechi et al. · PubMed · 1996 · 370 citations

Nude Rats, Medicinal Chemistry, Oncology +13

Preclinical antitumor efficacy of S-1: a new oral formulation of 5-fluorouracil on human tumor xenografts.

M Fukushima, Hirofumi Satake, Junji Uchida et al. · International Journal of Oncology · 1998 · 105 citations

Tumor Biology, Tumor Xenografts, Oncology +14

Augmentation of the chemotherapeutic effectiveness of UFT, a combination of tegafur [1-(2-tetrahydrofuryl)-5-fluorouracil] with uracil, by oral l-leucovorin.

Hiroyuki Okabe, Toshiyuki Toko, Hitoshi Saitô et al. · PubMed · 1997 · 23 citations

Pharmaceutical Science, Chemoprevention Strategy, Combined Modality +19