Marian Case

Ras pathway mutations are prevalent in relapsed childhood acute lymphoblastic leukemia and confer sensitivity to MEK inhibition

Julie Irving, Elizabeth Matheson, Lynne Minto et al. · Blood · 2014 · 257 citations · Full text

Medicine, Genetics, Oncology +17

A comprehensive analysis of the CDKN2A gene in childhood acute lymphoblastic leukemia reveals genomic deletion, copy number neutral loss of heterozygosity, and association with specific cytogenetic subgroups

Sarina Sulong, Anthony V. Moorman, Julie Irving et al. · Blood · 2008 · 223 citations

Life Sciences, Genetics, Molecular Genetics +16

Mutation of Genes Affecting the RAS Pathway Is Common in Childhood Acute Lymphoblastic Leukemia

Marian Case, Elizabeth Matheson, Lynne Minto et al. · Cancer Research · 2008 · 137 citations · Full text

Medicine, Genetics, Oncology +17

Establishment and validation of a standard protocol for the detection of minimal residual disease in B lineage childhood acute lymphoblastic leukemia by flow cytometry in a multi-center setting;

Julie Irving, Jenny Jesson, Paul Virgo et al. · Haematologica · 2009 · 101 citations · Full text

Medicine, Hematology, Oncology +17

Loss of Heterozygosity in Childhood Acute Lymphoblastic Leukemia Detected by Genome-Wide Microarray Single Nucleotide Polymorphism Analysis

Julie Irving, Lisa C. Bloodworth, Nick Bown et al. · Cancer Research · 2005 · 94 citations

Life Sciences, Genetics, Molecular Genetics +17