Isabelle Vande Broek

Migration of culture-expanded human mesenchymal stem cells through bone marrow endothelium is regulated by matrix metalloproteinase-2 and tissue inhibitor of metalloproteinase-3

Ann De Becker, Paul Van Hummelen, Marleen Bâkkus et al. · Haematologica · 2007 · 226 citations · Full text

Targeting the multiple myeloma hypoxic niche with TH-302, a hypoxia-activated prodrug

Jinsong Hu, Damian Handisides, Els Van Valckenborgh et al. · Blood · 2010 · 155 citations

Chemokine receptor CCR2 is expressed by human multiple myeloma cells and mediates migration to bone marrow stromal cell-produced monocyte chemotactic proteins MCP-1, -2 and -3

Isabelle Vande Broek, Kewal Asosingh, Karin Vanderkerken et al. · British Journal of Cancer · 2003 · 126 citations · Full text

Bortezomib Alone or in Combination with the Histone Deacetylase Inhibitor JNJ-26481585: Effect on Myeloma Bone Disease in the 5T2MM Murine Model of Myeloma

Sarah Deleu, Miguel Lemaire, Janine Arts et al. · Cancer Research · 2009 · 90 citations · Full text

Sclerostin, Proteasome Inhibitor Bortezomib, Pathology +17

Upregulation of miR-135b Is Involved in the Impaired Osteogenic Differentiation of Mesenchymal Stem Cells Derived from Multiple Myeloma Patients

Song Xu, Gaia Santini, Kim De Veirman et al. · PLoS ONE · 2013 · 81 citations · Full text

Immunology, Osteoporosis, Tumor Biology +17