M. Margarida Bernardo

Binding of Active (57 kDa) Membrane Type 1-Matrix Metalloproteinase (MT1-MMP) to Tissue Inhibitor of Metalloproteinase (TIMP)-2 Regulates MT1-MMP Processing and Pro-MMP-2 Activation

Sonia Hernandez‐Barrantes, Márta Tóth, M. Margarida Bernardo et al. · Journal of Biological Chemistry · 2000 · 310 citations · Full text

Life Sciences, Cell Biology, Apoptosis +9

Pro-MMP-9 activation by the MT1-MMP/MMP-2 axis and MMP-3: role of TIMP-2 and plasma membranes

Márta Tóth, Irina Chvyrkova, M. Margarida Bernardo et al. · Biochemical and Biophysical Research Communications · 2003 · 198 citations

Life Sciences, Biochemistry, Molecular Biology +4

Potent and Selective Mechanism-Based Inhibition of Gelatinases

Stephen H.M. Brown, M. Margarida Bernardo, Zhihong Li et al. · Journal of the American Chemical Society · 2000 · 196 citations

Medicine, Biochemistry, Pharmacology +11

TIMP-2 (tissue inhibitor of metalloproteinase-2) regulates MMP-2 (matrix metalloproteinase-2) activity in the extracellular environment after pro-MMP-2 activation by MT1 (membrane type 1)-MMP

M. Margarida Bernardo, Rafael Fridman · Biochemical Journal · 2003 · 195 citations · Full text

Medicine, Cancer Biology, Cell Biology +17

Tissue Inhibitor of Metalloproteinase-1 Protects Human Breast Epithelial Cells Against Intrinsic Apoptotic Cell Death via the Focal Adhesion Kinase/Phosphatidylinositol 3-Kinase and MAPK Signaling Pathway

M. Margarida Bernardo, Rafael Fridman, Hyeong-Reh Choi Kim · Journal of Biological Chemistry · 2003 · 177 citations · Full text

Life Sciences, Cell Biology, Oncology +16