A Genome-wide CRISPR Screen in Toxoplasma Identifies Essential Apicomplexan Genes

Saima Sidik, Diego Huet, Suresh M. Ganesan, +7

Cell

Off-target EffectNatural SciencesGeneticsGene CharacterizationGenome Engineering +8

Tagging of Endogenous Genes in a <i>Toxoplasma gondii</i> Strain Lacking Ku80

My‐Hang Huynh, Vern B. Carruthers

Eukaryotic Cell

A Cleavable Propeptide Influences<i>Toxoplasma</i>Infection by Facilitating the Trafficking and Secretion of the TgMIC2–M2AP Invasion Complex

Jill M. Harper, My‐Hang Huynh, Isabelle Coppens, +3

Molecular Biology of the Cell

Protein SecretionMicrobial PathogensImmunologyPathologyImmunologic Mechanism +22

Toxoplasma depends on lysosomal consumption of autophagosomes for persistent infection

Manlio Di Cristina, Zhicheng Dou, Matteo Lunghi, +13

Nature Microbiology

Cell AutophagyMitophagyParasitic ProtozoaPathogenesisImmunology +5

Toxoplasma gondii protease TgSUB1 is required for cell surface processing of micronemal adhesive complexes and efficient adhesion of tachyzoites

Vanessa Lagal, Emily M. Binder, My‐Hang Huynh, +7

Cellular Microbiology

Parasitic DiseaseProtein SecretionProteolytic TrimmingCell AdhesionImmunology +16

Toxoplasma gondii Cathepsin L Is the Primary Target of the Invasion-inhibitory Compound Morpholinurea-leucyl-homophenyl-vinyl Sulfone Phenyl

E.T. Larson, Fabiola Parussini, My‐Hang Huynh, +6

Journal of Biological Chemistry

Protein SecretionAntiparasitic AgentPathologyMolecular BiologyCytoskeleton +16

Activation of SPARC Expression in Reactive Stroma Associated with Human Epithelial Ovarian Cancer

Theodore J. Brown, Patricia A. Shaw, Xantha Karp, +3

Gynecologic Oncology

MedicineReactive Stroma AssociatedPathologyGynecologySparc Expression +5

RNG1 is a late marker of the apical polar ring in <i>Toxoplasma gondii</i>

Johnson Q. Tran, Jessica Cruz de Leon, Catherine Li, +3

Cytoskeleton

Apical PolarityMolecular BiologyCytoskeletonLate MarkerApical Polar Ring +15

Biochemical and molecular characterization of the pyrimidine biosynthetic enzyme dihydroorotate dehydrogenase from Toxoplasma gondii

Miryam Andrea Hortua Triana, My‐Hang Huynh, Manuel F. Garavito, +5

Molecular and Biochemical Parasitology

Molecular CharacterizationBiosynthesisCellular EnzymologyBiochemistryBiochemical Taxonomy +5

Trans-genera reconstitution and complementation of an adhesion complex in Toxoplasma gondii

My‐Hang Huynh, Corinna Opitz, Lai-Yu Kwok, +3

Cellular Microbiology

Trans-genera ReconstitutionMicroneme Protein Tgmic2Microbial PathogensGeneticsImmunology +14