INVESTIGATION IN MAN OF THE EFFICACY OF A BENZODIAZEPINE ANTAGONIST, Ro 15-1788

Austin Darragh, Mary Scully, Ronan Lambe, +3

The Lancet

Substance AbuseMedicinal ChemistryPsychoactive DrugPharmacological StudyRo 15-1788 +9

Comparison of the effects of I.C.I. 50172 and propranolol on the cardiovascular responses to adrenaline, isoprenaline and exercise

I. Brick, K.J. Hutchison, D. G. McDevitt, +2

British Journal of Pharmacology

RO 15‐1788 antagonises the central effects of diazepam in man without altering diazepam bioavailability.

A. Darragh, R. Lambe, Marie Kenny, +3

British Journal of Clinical Pharmacology

RO 15–1788 ANTAGONIZES THE EFFECTS OF DIAZEPAM IN MAN WITHOUT AFFECTING ITS BIOAVAILABILITY

Ciaran A. O’Boyle, R. Lambe, A. Darragh, +3

British Journal of Anaesthesia

Drug InteractionsMolecular PharmacologyPsychoactive DrugMedicinePsychopharmacology +5

Absence of central effects in man of the benzodiazepine antagonist Ro 15-1788

Austin Darragh, Ronan Lambe, Ciaran A. O’Boyle, +2

Psychopharmacology

Substance AbuseBenzodiazepine Antagonist RoPsychoactive DrugPsychiatryAddiction +9

Effects of propranolol on peripheral vessels in man

I. Brick, W. E. Glover, K.J. Hutchison, +1

The American Journal of Cardiology

ThrombosisHypertensionCardiovascular DiseasePhysiologyVascular Surgery +7

Tolerance of healthy volunteers to intravenous administration of the benzodiazepine antagonist Ro 15-1788

A. Darragh, R. Lambe, Marie Kenny, +1

European Journal of Clinical Pharmacology

Substance AbuseBenzodiazepine Antagonist RoDrug IntoleranceIntravenous AdministrationPsychoactive Drug +8

Antagonism of the central effects of 3‐methylclonazepam.

A. Darragh, R. Lambe, I. Brick, +1

British Journal of Clinical Pharmacology

Molecular PharmacologyMedicineNeuropharmacologyToxicologyPharmacotherapy +4

Pharmacokinetics and tolerance of enoxacin in healthy volunteers administered at a dosage of 400 mg twice daily for 14 days

S. E. Tsuei, Austin Darragh, I. Brick

Journal of Antimicrobial Chemotherapy

Steady StateActive Enoxacin CapsulesReceived Placebo TherapyHealthy VolunteersPharmacology +7

Stimulation of adrenergic beta-receptors by orciprenaline.

R.G. Shanks, I. Brick, K.J. Hutchison, +1

BMJ

Molecular PharmacologyAdrenal GlandAdrenergic Beta-receptorsMedicinePhysiology +3