A systematic, genome-wide, phenotype-driven mutagenesis programme for gene function studies in the mouse

Patrick M. Nolan, Jo Peters, Mark Strivens, +41

Nature Genetics

Knockout MouseTransgenic Mouse ModelsGeneticsPhenotype-driven Mutagenesis ProgrammeGene Characterization +9

Mutation of Celsr1 Disrupts Planar Polarity of Inner Ear Hair Cells and Causes Severe Neural Tube Defects in the Mouse

John A. Curtin, Elizabeth Quint, Vicky Tsipouri, +12

Current Biology

Molecular NeuroscienceDevelopmental BiologyGeneticsMorphogenesisNeurogenetics +4

Identification of the skeletal remains of a murder victim by DNA analysis

Erika Hagelberg, Ian C. Gray, Alec J. Jeffreys

Nature

Forensics AnalysisGeneticsForensic MedicineBiometricsDna Analysis +9

Loss of the chromosomal region 10q23-25 in prostate cancer.

Ian C. Gray, S.M.A. Phillips, S. J. Lee, +3

PubMed

EngineeringCytogeneticsGeneticsProstate AdenocarcinomaEpigenetics +14

The C9ORF72 expansion mutation is a common cause of ALS+/−FTD in Europe and has a single founder

Bradley Smith, Stephen Newhouse, Aleksey Shatunov, +43

European Journal of Human Genetics

Amyotrophic Lateral SclerosisGenetic DisorderGeneticsPathologyDegenerative Disease +6

A gene-driven ENU-based approach to generating an allelic series in any gene

Mohamed Mohideen Quwailid, Alison Hugill, Neil Dear, +27

Mammalian Genome

BiologyAllelic SeriesFunctional GenomicsEngineeringGenetics +12

A 2.4-Megabase Physical Map Spanning the CYP2C Gene Cluster on Chromosome 10q24

Ian C. Gray, Carlo Nobile, Rosella Muresu, +2

Genomics

ChromatinCytogeneticsGenetics2.4-Megabase Physical MapGenome Structure +10

Implementation of a large-scale ENU mutagenesis program: towards increasing the mouse mutant resource

Patrick M. Nolan, Jo Peters, Lucie Vizor, +18

Mammalian Genome

Knockout MouseGeneticsMolecular BiologyGenetic EngineeringMolecular Genetics +5

Evolutionary transience of hypervariable minisatellites in man and the primates

Ian C. Gray, Alec J. Jeffreys

Proceedings of the Royal Society B Biological Sciences

PrimatologyKin RecognitionGeneticsPrimate SystematicsGenetic Diversity +18

A mutation in Af4 is predicted to cause cerebellar ataxia and cataracts in the robotic mouse.

Adrian M. Isaacs, Peter L. Oliver, Emma Jones, +11

PubMed

Knockout MouseDevelopmental BiologyOphthalmologyExperimental OphthalmologyRobotic Mouse +9