Exploratory Study of Oral Combination Antiviral Therapy for Hepatitis C

Fred Poordad, Eric Lawitz, Kris V. Kowdley, +9

New England Journal of Medicine

<i>In Vitro</i> and <i>In Vivo</i> Antiviral Activity and Resistance Profile of Ombitasvir, an Inhibitor of Hepatitis C Virus NS5A

Preethi Krishnan, Jill Beyer, Neeta Mistry, +10

Antimicrobial Agents and Chemotherapy

Identification of host genes involved in hepatitis C virus replication by small interfering RNA technology

Teresa I. Ng, Hongmei Mo, Yupeng He, +9

Hepatology

Discovery of ABT-267, a Pan-Genotypic Inhibitor of HCV NS5A

David A. DeGoey, John T. Randolph, Dachun Liu, +26

Journal of Medicinal Chemistry

Excellent PotencyMedicinal ChemistryHcv Ns5aMedicineAntiviral Drug Development +9

Mutations Conferring Resistance to a Hepatitis C Virus (HCV) RNA-Dependent RNA Polymerase Inhibitor Alone or in Combination with an HCV Serine Protease Inhibitor In Vitro

Hongmei Mo, Liangjun Lu, Ron Pithawalla, +12

Antimicrobial Agents and Chemotherapy

Viral ReplicationHepatitis C VirusViral HepatitisCompounds A-782759Antiviral Therapy +10

<i>In Vitro</i> Activity and Resistance Profile of Dasabuvir, a Nonnucleoside Hepatitis C Virus Polymerase Inhibitor

Warren M. Kati, Gennadiy Koev, Michelle Irvin, +9

Antimicrobial Agents and Chemotherapy

Viral Polymerase StructureImmunologyAntiviral DrugDrug ResistanceViral Hepatitis +15

A Positive-Strand RNA Virus with Three Very Different Subgenomic RNA Promoters

Gennadiy Koev, W. Allen Miller

Journal of Virology

A phase 2a trial of 12-week interferon-free therapy with two direct-acting antivirals (ABT-450/r, ABT-072) and ribavirin in IL28B C/C patients with chronic hepatitis C genotype 1

Eric Lawitz, Fred Poordad, Kris V. Kowdley, +8

Journal of Hepatology

Hepatitis CViral HepatitisImmunologyAntiviral TherapyHepatitis +8

Primary and Secondary Structural Elements Required for Synthesis of Barley Yellow Dwarf Virus Subgenomic RNA1

Gennadiy Koev, B. R. Mohan, W. Allen Miller

Journal of Virology

The 3′-Terminal Structure Required for Replication of Barley Yellow Dwarf Virus RNA Contains an Embedded 3′ End

Gennadiy Koev, Sijun Liu, Randy Beckett, +1

Virology

Virus StructureViral ReplicationPlant VirusViral Polymerase StructureMedicine +11