Janus Kinase 2, an Early Target of α7 Nicotinic Acetylcholine Receptor-mediated Neuroprotection against Aβ-(1–42) Amyloid

Seán Shaw, Merouane Bencherif, Mario B. Marrero

Journal of Biological Chemistry

Inhibition of the JAK/STAT Signaling Pathway Prevents the High Glucose-Induced Increase in TGF-β and Fibronectin Synthesis in Mesangial Cells

Xiaodan Wang, Seán Shaw, Farhad Amiri, +2

Diabetes

Angiotensin II activation of the JAK/STAT pathway in mesangial cells is altered by high glucose

Farhad Amiri, Seán Shaw, Xiaodan Wang, +4

Kidney International

InflammationMetabolic SyndromeSignal TransductionHigh GlucoseDiabetes +11

Angiotensin II blockade prevents hyperglycemia-induced activation of JAK and STAT proteins in diabetic rat kidney glomeruli

Amy K. Banes, Seán Shaw, John Jenkins, +4

American Journal of Physiology-Renal Physiology

HypertensionAng IiAng Ii-InflammationMetabolic Syndrome +18

S100B-RAGE-Mediated Augmentation of Angiotensin II-Induced Activation of JAK2 in Vascular Smooth Muscle Cells Is Dependent on PLD2

Seán Shaw, Ann Marie Schmidt, Amy K. Banes, +3

Diabetes

High Glucose Augments the Angiotensin II-induced Activation of JAK2 in Vascular Smooth Muscle Cells via the Polyol Pathway

Seán Shaw, Xiaodan Wang, Heather Redd, +3

Journal of Biological Chemistry

Increased Oxidative and Nitrative Stress Accelerates Aging of the Retinal Vasculature in the Diabetic Retina

Folami Lamoke, Seán Shaw, Jianghe Yuan, +4

PLoS ONE

AgingBiogerontologyVascular Cell SenescenceOxidative StressDiabetic Retinopathy +15

The Neuroprotective Effect of 2-(3-Pyridyl)-1-azabicyclo[3.2.2]nonane (TC-1698), a Novel α7 Ligand, Is Prevented through Angiotensin II Activation of a Tyrosine Phosphatase

Mario B. Marrero, Roger L. Papke, Balwinder S. Bhatti, +2

Journal of Pharmacology and Experimental Therapeutics

Aldose reductase pathway mediates JAK‐STAT signaling: a novel axis in myocardial ischemic injury

Yuying C. Hwang, Seán Shaw, Michiyo Kaneko, +3

The FASEB Journal

Heart FailureAldose Reductase PathwayRedox BiologyOxidative StressJak2 Activation +16

Effect of simvastatin on high glucose- and angiotensin II-induced activation of the JAK/STAT pathway in mesangial cells

Amy Banes‐Berceli, Seán Shaw, Guochuan Ma, +6

American Journal of Physiology-Renal Physiology

ImmunologyAng IiOxidative StressJak2 ActivationInflammation +19