Role of p21 in Apoptosis and Senescence of Human Colon Cancer Cells Treated with Camptothecin

Zhiyong Han, Wenyi Wei, Stephen Dunaway, +7

Journal of Biological Chemistry

High ConcentrationChemoprevention StrategyNm CptMedicineLow Concentration +11

RKIP Sensitizes Prostate and Breast Cancer Cells to Drug-induced Apoptosis

Devasis Chatterjee, Yin Bai, Zhe Wang, +15

Journal of Biological Chemistry

Bortezomib Inhibits Nuclear Factor-κB–Dependent Survival and Has Potent <i>In vivo</i> Activity in Mesothelioma

Andrea Sartore‐Bianchi, Fabio Gasparri, Arturo Galvani, +7

Clinical Cancer Research

Concentrative uridine transport by murine splenocytes: kinetics, substrate specificity, and sodium dependency.

James W. Darnowski, Christina Holdridge, Robert E. Handschumacher

PubMed

Urd UptakeIsolated Murine SplenocytesCellular PhysiologyOxidative StressRenal Function +18

Tissue uridine pools: evidence in vivo of a concentrative mechanism for uridine uptake.

James W. Darnowski, Robert E. Handschumacher

PubMed

Urological ResearchRenal FunctionTissue Uridine PoolsMedicinePhysiology +12

5-Fluorouracil enhances azidothymidine cytotoxicity: in vitro, in vivo, and biochemical studies.

I. Brunetti, Alfredo Falcone, Peter A. Calabresi, +2

PubMed

Medicinal ChemistryTherapeutic EvaluationAllergyPyrimidine MetabolismPharmacological Study +11

Stat3 Cleavage by Caspases

James W. Darnowski, Frederick A. Goulette, Yingjie Guan, +4

Journal of Biological Chemistry

Transcriptional RegulationProtein FunctionSignal TransductionSignaling PathwayProtein Expression +13

Azidothymidine-induced cytotoxicity and incorporation into DNA in the human colon tumor cell line HCT-8 is enhanced by methotrexate in vitro and in vivo.

Patrizia Tosi, Peter A. Calabresi, Frederick A. Goulette, +2

PubMed

Tumor BiologyOncologyChemoprevention StrategyOncogenic AgentAzidothymidine-induced Cytotoxicity +12

Taurolidine Antiadhesive Properties on Interaction with E. coli; Its Transformation in Biological Environment and Interaction with Bacteria Cell Wall

Francesco Caruso, James W. Darnowski, Cristian Opazo, +4

PLoS ONE

Phase I clinical and pharmacological studies of benzylacyclouridine, a uridine phosphorylase inhibitor.

G Pizzorno, Lorrin Yee, Barbara Burtness, +8

PubMed

Molecular PharmacologyMedicinal ChemistryUrologyPharmacological StudiesMedicine +10