"Functional" Surgery in Subungual Melanoma

Matthias Moehrle, Silke Metzger, Wilfried Schippert, +3

Dermatologic Surgery

Localization of sequence variations in PGC-1α influence their modifying effect in Huntington disease

Hong Van B, Silke Metzger, Esteban Portal, +2

Molecular Neurodegeneration

Age at onset in Huntington’s disease is modified by the autophagy pathway: implication of the V471A polymorphism in Atg7

Silke Metzger, Meiju Saukko, H l ne Cao Van, +3

Human Genetics

Cell AutophagyNeurodegenerative DiseasesDevelopmental BiologyGenetic DisorderGenetics +7

A Novel BACHD Transgenic Rat Exhibits Characteristic Neuropathological Features of Huntington Disease

Libo Yu-Taeger, Elisabeth Petrasch‐Parwez, Alexander P. Osmand, +10

Journal of Neuroscience

GeneticsNeurochemical BiomarkersMolecular GeneticsDopamine Receptor BindingExperimental Neuropathology +15

Activation of AMPK-induced autophagy ameliorates Huntington disease pathology in vitro

Carolin Walter, Laura E. Clemens, Amelie J. Müller, +4

Neuropharmacology

Cell AutophagyNeurodegenerative DiseasesMitophagyDevelopmental BiologySignal Transduction +11

The V471A Polymorphism in Autophagy-Related Gene ATG7 Modifies Age at Onset Specifically in Italian Huntington Disease Patients

Silke Metzger, Carolin Walter, Raymund A.C. Roos, +2

PLoS ONE

GeneticsGenetic EpidemiologyHuman PolymorphismPathologyDisease Gene Identification +16

The S18Y polymorphism in the UCHL1 gene is a genetic modifier in Huntington’s disease

Silke Metzger, Peter Bauer, Juergen Tomiuk, +25

Neurogenetics

Genetic DisorderGeneticsHuman PolymorphismMolecular BiologyS18y Polymorphism +5

Genetic analysis of candidate genes modifying the age-at-onset in Huntington’s disease

Silke Metzger, Peter Bauer, Jürgen Tomiuk, +25

Human Genetics

Genetic AnalysisNeurodegenerative DiseasesCandidate GenesDevelopmental BiologyHuntington ’ +9

“Functional” Surgery in Subungual Melanoma

Matthias Moehrle, Silke Metzger, Wilfried Schippert, +3

Dermatologic Surgery

Limited ExcisionSurgical OncologySurgical PathologyMelanomaMelanoma Registry +8

Age‐dependent gene expression profile and protein expression in a transgenic rat model of Huntington's disease

Huu Phuc Nguyen, Silke Metzger, Carsten Holzmann, +4

PROTEOMICS - CLINICAL APPLICATIONS

Knockout MouseTranscriptional RegulationNeurodegenerative DiseasesDevelopmental BiologyProtein Expression +11