Binding and metabolism of platelet-activating factor by human neutrophils.

Joseph T. O’Flaherty, J R Surles, J F Redman, +3

Journal of Clinical Investigation

Proteinlipid InteractionHuman Polymorphonuclear NeutrophilsDissociation ConstantImmunologyGlycobiology +19

1-0-alkyl-2-N-methylcarbamyl-glycerophosphocholine: A biologically potent, non-metabolizable analog of platelet-activating factor

Joseph T. O’Flaherty, J F Redman, Jeffrey D. Schmitt, +5

Biochemical and Biophysical Research Communications

BiochemistryMedicineMechanism Of ActionPharmacological AgentPlatelet-activating Factor +2

Tumor necrosis factor-alpha regulates expression of receptors for formyl-methionyl-leucyl-phenylalanine, leukotriene B4, and platelet-activating factor. Dissociation from priming in human polymorphonuclear neutrophils

Joseph T. O’Flaherty, Adriano G. Rossi, J F Redman, +1

The Journal of Immunology

5-Oxo-Eicosatetraenoate, a Potent Human Neutrophil Stimulus

Joseph T. O’Flaherty, John F. Cordes, J F Redman, +1

Biochemical and Biophysical Research Communications

InflammationAnti-inflammatoryOxysterolGranulocyteMedicine +4

Translocation of protein kinase C in human polymorphonuclear neutrophils. Regulation by cytosolic Ca2(+)-independent and Ca2(+)-dependent mechanisms.

Joseph T. O’Flaherty, D P Jacobson, J F Redman, +1

Journal of Biological Chemistry

Human Polymorphonuclear NeutrophilsImmunologyCellular PharmacologyPmn BindingCellular Physiology +17

Roles of Ca2+ in human neutrophil responses to receptor agonists

Joseph T. O’Flaherty, Adriano G. Rossi, D P Jacobson, +1

Biochemical Journal

Bidirectional Effects of Protein Kinase C Activators

Joseph T. O’Flaherty, D P Jacobson, J F Redman

Journal of Biological Chemistry

PharmacotherapyCellular PhysiologySignaling PathwayReceptor Tyrosine KinaseCa2+ Transients +15

Metabolism of 5-hydroxyicosatetraenoate by human neutrophils: production of a novel omega-oxidized derivative.

Joseph T. O’Flaherty, Robert L. Wykle, J F Redman, +2

The Journal of Immunology

Bioorganic ChemistryLipid PeroxidationNovel Omega-oxidized DerivativeArachidonic Acid MetabolitesRedox Biology +19

Mechanism involved in the mobilization of neutrophil calcium by 5-hydroxyeicosatetraenoate.

Joseph T. O’Flaherty, D P Jacobson, J F Redman

The Journal of Immunology

Comparison of 1-O-alkyl-, 1-O-alk-1'-enyl-, and 1-O-acyl-2-acetyl-sn-glycero-3-phosphoethanolamines and -3-phosphocholines as agonists of the platelet-activating factor family

Joseph T. O’Flaherty, Teresa G. Tessner, D G Greene, +2

Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism

ThrombopoiesisThrombosisBiochemistryBlood PlateletMedicine +4