Binding of the antagonist []candesartan to angiotensin II AT1 receptor-tranfected Chinese hamster ovary cells

Frederik Fierens, Patrick Vanderheyden, Jean-Paul De Backer, +1

European Journal of Pharmacology

InflammationMolecular PharmacologyMedicineHormonal ReceptorPhysiology +5

A two-state receptor model for the interaction between angiotensin II type 1 receptors and non-peptide antagonists

Georges Vauquelin, Peter Morsing, Frederik Fierens, +2

Biochemical Pharmacology

Signal TransductionFunctional SelectivityMedicinePhysiologyReceptor (Biochemistry) +6

Dopamine agonists used in the treatment of Parkinson's disease and their selectivity for the D1, D2, and D3 dopamine receptors in human striatum

Jacques De Keyser, Jean-Paul De Backer, Nadine Wilczak, +1

Progress in Neuro-Psychopharmacology and Biological Psychiatry

D3 Dopamine ReceptorsHuman StriatumFunctional SelectivityMedicineNeuropharmacology +7

Distinct binding properties of the AT1 receptor antagonist [3H]candesartan to intact cells and membrane preparations

Frederik Fierens, Patrick Vanderheyden, Chantal Roggeman, +3

Biochemical Pharmacology

Molecular PharmacologyMembrane PreparationsMolecular PhysiologyBiochemistryG Protein-coupled Receptor +7

D2 dopamine receptors in the human brain: heterogeneity based on differences in guanine nucleotide effect on agonist binding, and their presence on corticostriatal nerve terminals

Jacques De Keyser, Hilde Walraevens, Jean-Paul De Backer, +2

Brain Research

Agonist BindingFunctional SelectivityNeuroanatomyMedicineNeurotransmitter +10

Coupling of D1 dopamine receptors to the guanine nucleotide binding protein Gs is deficient in Huntington's disease

Jacques De Keyser, Jean-Paul De Backer, Guy Ebinger, +1

Brain Research

Functional SelectivityGeneticsProtein GsMolecular BiologyNeuropharmacology +7

Pharmacological characterization of I1 and I2 imidazoline receptors in human striatum

Anja Flamez, Jean-Paul De Backer, Eva Czerwiec, +2

Neurochemistry International

Human StriatumPharmacological CharacterizationBiochemistryMedicineMechanism Of Action +6

[3H]Clozapine is not a suitable radioligand for the labelling of D4 dopamine receptors in postmortem human brain

Anja Flamez, Jean-Paul De Backer, Nadine Wilczak, +2

Neuroscience Letters

NeuropsychologyPsychiatryNeuroanatomyD4 Dopamine ReceptorsSchizophrenia +9

Role of basic amino acids of the human angiotensin type 1 receptor in the binding of the non-peptide antagonist candesartan

Georges Vauquelin, Frederik Fierens, Zsuzsanna Gáborik, +4

Journal of the Renin-Angiotensin-Aldosterone System

HypertensionAmino AcidsBasic Amino AcidsPharmacotherapyAng Ii +17

Non-competitive binding of the nonpeptide antagonist BIBP3226 to rat forebrain neuropeptide Y1 receptors

Patrick Vanderheyden, Isabelle Van Liefde, Jean-Paul De Backer, +1

European Journal of Pharmacology

Non-competitive BindingFunctional SelectivityMedicinePhysiologyReceptor (Biochemistry) +9