The role of Ca2+ in baicalein-induced apoptosis in human breast MDA-MB-231 cancer cells through mitochondria- and caspase-3-dependent pathway.

Jau Hong Lee, Yu Ching Li, Siu Wan Ip, +9

PubMed

Breast OncologyChemoprevention StrategyApoptosisCell DeathBaicalein-induced Apoptosis +18

Berberine induces apoptosis in human HSC-3 oral cancer cells via simultaneous activation of the death receptor-mediated and mitochondrial pathway.

Chin Chung Lin, Jai‐Sing Yang, Jin Tang Chen, +8

PubMed

Berberine Induces ApoptosisChemoprevention StrategyApoptosisCell DeathTumor Biology +15

Down-regulation of cyclin B1 and up-regulation of Wee1 by berberine promotes entry of leukemia cells into the G2/M-phase of the cell cycle.

Chin Chung Lin, Shuw Yun Lin, Jing‐Gung Chung, +3

PubMed

Chemoprevention StrategyCell DeathLeukemia CellsCyclin B1Pharmacotherapy +15

Apoptosis of human leukemia HL-60 cells and murine leukemia WEHI-3 cells induced by berberine through the activation of caspase-3.

Chin Chung Lin, Shung Te Kao, Guang Wei Chen, +2

PubMed

Berberine-induced ApoptosisBiochemistryMitochondrial FunctionMedicineChemoprevention Strategy +13

The roles of endoplasmic reticulum stress and Ca2+ on rhein-induced apoptosis in A-549 human lung cancer cells.

Te Chun Hsia, Jai‐Sing Yang, Guang Wei Chen, +8

PubMed

Chemoprevention StrategyLung InflammationApoptosisCell DeathPathology +19

Diallyl disulfide inhibits WEHI-3 leukemia cells in vivo.

Jai‐Sing Yang, Lai‐Fong Kok, Yu Lin, +7

PubMed

Chemoprevention StrategyImmunotoxicologyLipid PeroxidationApoptosisImmunology +15

Chrysin, a natural and biologically active flavonoid, influences a murine leukemia model in vivo through enhancing populations of T-and B-cells, and promoting macrophage phagocytosis and NK cell cytotoxicity.

Chin Chung Lin, Chun Shu Yu, Jai‐Sing Yang, +5

PubMed

Chemoprevention StrategyApoptosisImmunologyImmune RegulationCell Death +19

Extract of Hedyotis diffusa Willd influences murine leukemia WEHI-3 cells in vivo as well as promoting T- and B-cell proliferation in leukemic mice.

Chin Chung Lin, Chao Lin Kuo, Mau Hva Lee, +9

PubMed

ImmunotoxicologyLymphocyte DevelopmentEnlarged SpleenImmune RegulationImmunology +14

Crude extracts of Euchresta formosana radix inhibit invasion and migration of human hepatocellular carcinoma cells.

Shu Chun Hsu, Chao Lin Kuo, Jing Lin, +5

PubMed

Chemoprevention StrategyPathologyCell DeathTumor BiologyHepatobiliary Tumor +17

Berberine decreased N-acetylation of 2-aminofluorene through inhibition of N-acetyltransferase gene expression in human leukemia HL-60 cells.

Chin Chung Lin, Shung Te Kao, Guang Wei Chen, +1

PubMed

Nat Gene ExpressionChemoprevention StrategyBiochemistryOncogenic AgentN-acetyltransferase Gene Expression +8