Cooperation between p21 and Akt is required for p53‐dependent cellular senescence

Young Yeon Kim, Hye Jin Jee, Jee‐Hyun Um, +3

Aging Cell

Assessment of mitophagy in mt‐Keima <i>Drosophila</i> revealed an essential role of the PINK1‐Parkin pathway in mitophagy induction <i>in vivo</i>

Young Yeon Kim, Jee‐Hyun Um, Jeong‐Hyun Yoon, +12

The FASEB Journal

Nek6 overexpression antagonizes p53-induced senescence in human cancer cells

Hye Jin Jee, Ae Jeong Kim, Naree Song, +4

Cell Cycle

Nek6 is involved in G₂/M phase cell cycle arrest through DNA damage-induced phosphorylation

Min‐Young Lee, Hyun‐Ju Kim, Myoung-Ae Kim, +6

Cell Cycle

Melatonin suppresses doxorubicin‐induced premature senescence of A549 lung cancer cells by ameliorating mitochondrial dysfunction

Naree Song, Ae Jeong Kim, Hyun‐Ju Kim, +4

Journal of Pineal Research

Chemoprevention StrategyMitochondrial DysfunctionCell DeathCancer BiologyMelatonin Suppresses +15

Loss of Med1/TRAP220 promotes the invasion and metastasis of human non-small-cell lung cancer cells by modulating the expression of metastasis-related genes

Hyunju Kim, Mee Sook Roh, Choon Hee Son, +7

Cancer Letters

Metastasis-related GenesMedicineCell BiologyTumor SuppressorCancer Genetics +5

Akt3 knockdown induces mitochondrial dysfunction in human cancer cells

Minjee Kim, Young Yeon Kim, Hye Jin Jee, +4

Acta Biochimica et Biophysica Sinica

Tumor BiologyHuman Cancer CellsProper Mitochondrial RespirationMitochondrial FunctionMedicine +7

Nek6 suppresses the premature senescence of human cancer cells induced by camptothecin and doxorubicin treatment

Hye Jin Jee, Hyun-Ju Kim, Ae Jeong Kim, +3

Biochemical and Biophysical Research Communications

The inhibition of Nek6 function sensitizes human cancer cells to premature senescence upon serum reduction or anticancer drug treatment

Hye Jin Jee, Hyun‐Ju Kim, Ae Jeong Kim, +4

Cancer Letters

Serum ReductionMedicineCell DeathCellular SenescenceTumor Suppressor +7

UV light induces premature senescence in Akt1-null mouse embryonic fibroblasts by increasing intracellular levels of ROS

Hye Jin Jee, Hyun‐Ju Kim, Ae Jeong Kim, +3

Biochemical and Biophysical Research Communications

Intracellular LevelsDevelopmental BiologyInduces Premature SenescencePhotocarcinogenesisExtracellular Matrix +7