R A de Melker

The end of antibiotic treatment in adults with acute sinusitis-like complaints in general practice? A placebo-controlled double-blind randomized doxycycline trial.

W.A.B. Stalman, Gerrit A. van Essen, Y. van der Graaf et al. · PubMed · 1997 · 105 citations · Full text

Medicine, Otolaryngology, Pharmacotherapy +13

Is immunising all patients with chronic lung disease in the community against influenza cost effective? Evidence from a general practice based clinical prospective cohort study in Utrecht, The Netherlands.

Eelko Hak, Gerrit A. van Essen, Erik Buskens et al. · Journal of Epidemiology & Community Health · 1998 · 93 citations · Full text

Veterinary Medicine, Infectious Diseases, Preventive Medicine +17

Co-amoxiclav in recurrent acute otitis media: placebo controlled study.

Cees L. Appelman, Johannes Q.P.J. Claessen, F Touw-Otten et al. · BMJ · 1991 · 90 citations · Full text

Medicine, Otolaryngology, Pharmacotherapy +12

Do patients with sore throat benefit from penicillin? A randomized double-blind placebo-controlled clinical trial with penicillin V in general practice.

C. F. Dagnelie, Y. van der Graaf, R A de Melker · PubMed · 1996 · 82 citations

Life Sciences, Microbiology, Pharmacotherapy +13

A cross-national study of acute otitis media: risk factors, severity, and treatment at initial visit. Report from the International Primary Care Network (IPCN) and the Ambulatory Sentinel Practice Network (ASPN).

Larry Culpepper, L A Green, R A de Melker et al. · PubMed · 2002 · 74 citations

Medicine, Infectious Diseases, Otolaryngology +13