CD8+ T Cell Immunity Against a Tumor/Self-Antigen Is Augmented by CD4+ T Helper Cells and Hindered by Naturally Occurring T Regulatory Cells

Paul A. Antony, Ciriaco A. Piccirillo, Steven E. Finkelstein, +8

The Journal of Immunology

Vaccination with a recombinant vaccinia virus encoding a “self” antigen induces autoimmune vitiligo and tumor cell destruction in mice: Requirement for CD4⁺T lymphocytes

Willem W. Overwijk, David Lee, Deborah R. Surman, +7

Proceedings of the National Academy of Sciences

Microbiota-Dependent Activation of an Autoreactive T Cell Receptor Provokes Autoimmunity in an Immunologically Privileged Site

Reiko Horai, Carlos R. Zárate-Bladés, Patrícia Dillenburg-Pilla, +8

Immunity

InflammationAllergyAutoimmune DiseaseT-regulatory CellImmunology +9

Noncanonical Autophagy Promotes the Visual Cycle

Jiyoung Kim, Hui Zhao, Jennifer Martinez, +8

Cell

Cell AutophagyMitophagyNoncanonical AutophagyAutophagyMorphogenesis +4

Calcitriol Suppresses Antiretinal Autoimmunity through Inhibitory Effects on the Th17 Effector Response

Jun Tang, Ru Zhou, Dror Luger, +7

The Journal of Immunology

Th17 LineageT-regulatory CellImmune RegulationImmunologyImmunologic Mechanism +15

Blood-retinal barrier (BRB) breakdown in experimental autoimmune uveoretinitis: Comparison with vascular endothelial growth factor, tumor necrosis factor ?, and interleukin-1?-mediated breakdown

José D. Luna, Chi-Chao Chan, Nancy L. Derevjanik, +6

Journal of Neuroscience Research

Ocular DiseaseImmunologyImmune RegulationCell DeathPosterior Retina +24

Hypomethylation of the IL17RC Promoter Associates with Age-Related Macular Degeneration

Lai Wei, Baoying Liu, Jingsheng Tuo, +23

Cell Reports

32 Cases of Sympathetic Ophthalmia

Chi-Chao Chan

Archives of Ophthalmology

Essential Role of the MyD88 Pathway, but Nonessential Roles of TLRs 2, 4, and 9, in the Adjuvant Effect Promoting Th1-Mediated Autoimmunity

Shao Bo Su, Phyllis B. Silver, Rafael S. Grajewski, +4

The Journal of Immunology

Adaptive Immune SystemAdjuvant EffectInnate Immune SystemImmunologyImmune Regulation +18

Effective tumor treatment targeting a melanoma/melanocyte-associated antigen triggers severe ocular autoimmunity

Douglas C. Palmer, Chi-Chao Chan, Luca Gattinoni, +11

Proceedings of the National Academy of Sciences