Selective Blockade of the Capsaicin Receptor TRPV1 Attenuates Bone Cancer Pain

Joseph R. Ghilardi, Heidi Röhrich, Theodore H. Lindsay, +13

Journal of Neuroscience

Pain TherapyPain MedicineImmunologyMolecular PainSelective Blockade +15

Anti-NGF therapy profoundly reduces bone cancer pain and the accompanying increase in markers of peripheral and central sensitization

Molly A. Sevcik, Joseph R. Ghilardi, Christopher M. Peters, +8

Pain

Pain TherapyTumor InnervationPain MedicineNeuropathic PainMolecular Pain +22

Intravenous paclitaxel administration in the rat induces a peripheral sensory neuropathy characterized by macrophage infiltration and injury to sensory neurons and their supporting cells

Christopher M. Peters, Juan Miguel Jiménez‐Andrade, Beth M. Jonas, +5

Experimental Neurology

InflammationPeripheral SensoryPeripheral Nerve InjuryNeurophysiologyNeuroanatomy +11

A Blocking Antibody to Nerve Growth Factor Attenuates Skeletal Pain Induced by Prostate Tumor Cells Growing in Bone

Kyle G. Halvorson, Kazufumi Kubota, Molly A. Sevcik, +7

Cancer Research

Pain DisordersSclerostinTumor InnervationPain MedicineImmunology +22

Tumor-induced injury of primary afferent sensory nerve fibers in bone cancer pain

Christopher M. Peters, Joseph R. Ghilardi, Cathy P. Keyser, +7

Experimental Neurology

Health SciencesPeripheral Nerve InjuryPain MedicineMedicineNeuropathic Pain +10

Repeated dosing of ABT-102, a potent and selective TRPV1 antagonist, enhances TRPV1-mediated analgesic activity in rodents, but attenuates antagonist-induced hyperthermia

Prisca Honoré, Prasant Chandran, Gricelda Hernandez, +23

Pain

Pancreatic cancer pain and its correlation with changes in tumor vasculature, macrophage infiltration, neuronal innervation, body weight and disease progression

Theodore H. Lindsay, Beth M. Jonas, Molly A. Sevcik, +9

Pain

Tumor InnervationPain MedicineImmunologyPathologyMolecular Pain +16

Bone cancer pain: the effects of the bisphosphonate alendronate on pain, skeletal remodeling, tumor growth and tumor necrosis

Molly A. Sevcik, Nancy M. Luger, David B. Mach, +8

Pain

Pain MedicineOsteoporosisOrthopaedic SurgeryVivo Mouse ModelBone Morphogenic Protein +14

Endogenous Opioids Inhibit Early-Stage Pancreatic Pain in a Mouse Model of Pancreatic Cancer

Molly A. Sevcik, Beth M. Jonas, Theodore H. Lindsay, +6

Gastroenterology

Molecular PharmacologyPancreatic CancerPain MedicineMedicineMolecular Pain +4

Analgesic Efficacy of Bradykinin B1 Antagonists in a Murine Bone Cancer Pain Model

Molly A. Sevcik, Joseph R. Ghilardi, Kyle G. Halvorson, +3

Journal of Pain