Amino Acid Conjugates of Lithocholic Acid As Antagonists of the EphA2 Receptor

Matteo Incerti, Massimiliano Tognolini, Simonetta Russo, +11

Journal of Medicinal Chemistry

Peptide ScienceExperimental PharmacologyMolecular PharmacologyAnti-cancer AgentEph Receptor-ephrin System +16

Irreversible Inhibition of Epidermal Growth Factor Receptor Activity by 3-Aminopropanamides

Caterina Carmi, Elena Galvani, Federica Vacondio, +11

Journal of Medicinal Chemistry

Acrylamide AnaloguesAcrylamide FragmentPharmacotherapyTumor BiologyMolecular Pharmacology +14

<scp>U</scp>ni<scp>PR</scp>129 is a competitive small molecule <scp>E</scp>ph‐ephrin antagonist blocking <i>in vitro</i> angiogenesis at low micromolar concentrations

Iftiin Hassan‐Mohamed, Carmine Giorgio, Matteo Incerti, +10

British Journal of Pharmacology

Structure–Activity Relationships and Mechanism of Action of Eph–ephrin Antagonists: Interaction of Cholanic Acid with the EphA2 Receptor

Massimiliano Tognolini, Matteo Incerti, Iftiin Hassan‐Mohamed, +11

ChemMedChem

Chemical BiologyStructure–activity RelationshipsTumor BiologyMolecular PharmacologyAnti-cancer Agent +15

Metadynamics for Perspective Drug Design: Computationally Driven Synthesis of New Protein–Protein Interaction Inhibitors Targeting the EphA2 Receptor

Matteo Incerti, Simonetta Russo, Donatella Callegari, +10

Journal of Medicinal Chemistry

Drug TargetEngineeringMeta-d SimulationsDriven SynthesisMolecular Design +18

Target Hopping as a Useful Tool for the Identification of Novel EphA2 Protein–Protein Antagonists

Massimiliano Tognolini, Matteo Incerti, Daniele Pala, +5

ChemMedChem

Pharmacological evaluation of new bioavailable small molecules targeting Eph/ephrin interaction

Carmine Giorgio, Matteo Incerti, Miriam Corrado, +9

Biochemical Pharmacology

Molecular PharmacologyPharmaceutical ScienceAnti-inflammatoryPharmacological StudyEph/ephrin Interaction +7

Exploiting Free‐Energy Minima to Design Novel EphA2 Protein–Protein Antagonists: From Simulation to Experiment and Return

Simonetta Russo, Donatella Callegari, Matteo Incerti, +11

Chemistry - A European Journal

Synthesis and Structure-Activity Relationships of Amino Acid Conjugates of Cholanic Acid as Antagonists of the EphA2 Receptor

Simonetta Russo, Matteo Incerti, Massimiliano Tognolini, +11

Molecules

Combining Ligand- and Structure-Based Approaches for the Discovery of New Inhibitors of the EPHA2–ephrin-A1 Interaction

Daniele Pala, Riccardo Castelli, Matteo Incerti, +9

Journal of Chemical Information and Modeling

Drug TargetNew InhibitorsPharmacotherapyEph Receptor A2Tumor Biology +17