RhoA/Rho-Kinase Contribute to the Pathogenesis of Diabetic Renal Disease

Fang-Fang Peng, Dongcheng Wu, Bo Gao, +5

Diabetes

PKC-β1 Mediates Glucose-Induced Akt Activation and TGF-β1 Upregulation in Mesangial Cells

Dongcheng Wu, Fang-Fang Peng, Baifang Zhang, +5

Journal of the American Society of Nephrology

TGFβ-induced RhoA activation and fibronectin production in mesangial cells require caveolae

Fang-Fang Peng, Baifang Zhang, Dongcheng Wu, +3

American Journal of Physiology-Renal Physiology

Fibronectin ProductionCell ProliferationTgfbeta ReceptorCell GrowthCellular Physiology +20

RhoA Activation in Mesangial Cells by Mechanical Strain Depends on Caveolae and Caveolin-1 Interaction

Fang-Fang Peng, Dongcheng Wu, Alistair J. Ingram, +3

Journal of the American Society of Nephrology

Rhoa ActivationCytoskeletonMechanotransductionCellular PhysiologyOxidative Stress +22

Mechanical Strain-Induced RhoA Activation Requires NADPH Oxidase-Mediated ROS Generation in Caveolae

Ying Zhang, Fang-Fang Peng, Bo Gao, +2

Antioxidants and Redox Signaling

Nadph OxidaseLipid PeroxidationReactive Oxygen SpeciesRedox BiologyCellular Physiology +20

Akt Mediates Mechanical Strain-Induced Collagen Production by Mesangial Cells

Joan C. Krepinsky, Yanxia Li, Yanfei Chang, +6

Journal of the American Society of Nephrology

Hz Cyclic StrainCellular PhysiologyInflammationReceptor Tyrosine KinaseMesangial Cells +14

Regulator of calcineurin 1 deletion attenuates mitochondrial dysfunction and apoptosis in acute kidney injury through JNK/Mff signaling pathway

Jing‐Jie Xiao, Qing Liu, Ying Li, +7

Cell Death and Disease

Mechanical stretch-induced RhoA activation is mediated by the RhoGEF Vav2 in mesangial cells

Fang-Fang Peng, Baifang Zhang, Alistair J. Ingram, +3

Cellular Signalling

EngineeringCytoskeletonMechanotransductionCellular PhysiologyBiomechanics +14

Akt and RhoA activation in response to high glucose require caveolin-1 phosphorylation in mesangial cells

Suzhen Wu, Fang-Fang Peng, Jialin Li, +3

American Journal of Physiology-Renal Physiology

Src KinasePkc-β1 Membrane TranslocationRenal PathologyRhoa ActivationCaveolin-1 Phosphorylation +25

Staurosporine induces apoptosis in NG108-15 cells.

Baifang Zhang, Fang-Fang Peng, Jiang-Zhou Zhang, +1

PubMed