Mitochondrial Susceptibility to Oxidative Stress Exacerbates Cerebral Infarction That Follows Permanent Focal Cerebral Ischemia in Mutant Mice with Manganese Superoxide Dismutase Deficiency

Kensuke Murakami, Takeo Kondo, Makoto Kawase, +4

Journal of Neuroscience

Brain infarction is not reduced in SOD-1 transgenic mice after a permanent focal cerebral ischemia

Pak H. Chan, Hideyuki Kamii, Guo‐Yuan Yang, +4

Neuroreport

The development of a new mouse model of global ischemia: focus on the relationships between ischemia duration, anesthesia, cerebral vasculature, and neuronal injury following global ischemia in mice

Kensuke Murakami, Takeo Kondo, Makoto Kawase, +1

Brain Research

Cerebral Vascular RegulationIschemic StrokeNeurophysiologyGlobal IschemiaMedicine +13

Mild intraischemic hypothermia suppresses consumption of endogenous antioxidants after temporary focal ischemia in rats

Hiroshi Karibe, Sylvia F. Chen, Gregory J. Zarow, +4

Brain Research

Endogenous AntioxidantsReperfusion InjuryMedicineLipid PeroxidationPhysiology +9

The cytosolic antioxidant, copper/zinc superoxide dismutase, attenuates blood–brain barrier disruption and oxidative cellular injury after photothrombotic cortical ischemia in mice

Gyung Whan Kim, Anders Lewén, J. C. Copin, +2

Neuroscience

InflammationRedox SignalingReperfusion InjuryMedicineCopper/zinc Superoxide Dismutase +13

Oxidative Stress and Neuronal DNA Fragmentation Mediate Age-Dependent Vulnerability to the Mitochondrial Toxin, 3-Nitropropionic Acid, in the Mouse Striatum

Gyung Whan Kim, Pak H. Chan

Neurobiology of Disease

Mouse StriatumBiochemistryMitochondrial FunctionNeuropharmacologyDegenerative Pathology +7

Reduced mitochondrial manganese-superoxide dismutase activity exacerbates glutamate toxicity in cultured mouse cortical neurons

Yibing Li, Jean-Christophe Copin, Liza Reola, +6

Brain Research

Cell DeathExtracellular GlutamateGlutamate TreatmentRedox BiologySocial Sciences +14

Astrocytes overexpressing Cu,Zn superoxide dismutase have increased resistance to oxidative injury

Yongmei Chen, Pak H. Chan, Raymond A. Swanson

Glia

Occurrence of apoptosis following cold injury-induced brain edema in mice

Kensuke Murakami, T. Kondo, Shuzo Sato, +2

Neuroscience

InflammationHyperthermiaApoptosisImmunologyCell Death +7

Reduction of copper,zinc-superoxide dismutase in knockout mice does not affect edema or infarction volumes and the early release of mitochondrial cytochrome c after permanent focal cerebral ischemia

Miki Fujimura, Yuiko Morita‐Fujimura, Jean‐Christophe Copin, +2

Brain Research

Mitochondrial Cytochrome CIschemic StrokeMedicinePharmacologyKnockout Mice +12