Panitumumab and irinotecan versus irinotecan alone for patients with KRAS wild-type, fluorouracil-resistant advanced colorectal cancer (PICCOLO): a prospectively stratified randomised trial

Sarah Brown, Gary Middleton, Tim Maughan, +17

The Lancet Oncology

Tumor Stage After Neoadjuvant Chemotherapy Determines Survival After Surgery for Adenocarcinoma of the Esophagus and Esophagogastric Junction

Andrew Davies, James Gossage, Janine Zylstra, +7

Journal of Clinical Oncology

Tumor Necrosis Factor α As a New Target for Renal Cell Carcinoma: Two Sequential Phase II Trials of Infliximab at Standard and High Dose

Michelle Harrison, Eva Obermueller, Nick Maisey, +15

Journal of Clinical Oncology

Assessment of sarcopenia and changes in body composition after neoadjuvant chemotherapy and associations with clinical outcomes in oesophageal cancer

Connie Yip, Vicky Goh, Andrew Davies, +10

European Radiology

Surgical OncologyEsophageal CancerGastrointestinal OncologySarcopeniaMedicine +11

Efficacy of Reduced-Intensity Chemotherapy With Oxaliplatin and Capecitabine on Quality of Life and Cancer Control Among Older and Frail Patients With Advanced Gastroesophageal Cancer

Peter Hall, Daniel Swinson, David A. Cairns, +29

JAMA Oncology

Multicenter Randomized Phase III Trial Comparing Protracted Venous Infusion (PVI) Fluorouracil (5-FU) With PVI 5-FU Plus Mitomycin in Inoperable Pancreatic Cancer

Nick Maisey, Ian Chau, David Cunningham, +7

Journal of Clinical Oncology

Exercise prehabilitation during neoadjuvant chemotherapy may enhance tumour regression in oesophageal cancer: results from a prospective non-randomised trial

Janine Zylstra, Greg Whyte, Kerri Beckmann, +16

British Journal of Sports Medicine

Pathologic Lymph Node Regression After Neoadjuvant Chemotherapy Predicts Recurrence and Survival in Esophageal Adenocarcinoma: A Multicenter Study in the United Kingdom

J. Moore, Michael Green, Aida Santaolalla, +52

Journal of Clinical Oncology

Considerations when choosing oral chemotherapy: identifying and responding to patient need

Sheeba Irshad, Nick Maisey

European Journal of Cancer Care

OncologyCancer TherapeuticsCancer ManagementMetronomic TherapyPharmacology +13

A randomised phase III trial of the pharmacokinetic biomodulation of irinotecan using oral ciclosporin in advanced colorectal cancer: Results of the Panitumumab, Irinotecan & Ciclosporin in COLOrectal cancer therapy trial (PICCOLO)

Gary Middleton, Sarah Brown, Catherine Lowe, +16

European Journal of Cancer

MedicinePharmacologyColorectal CancerOral CiclosporinPharmacotherapy +6