Identification of ADAM10 as a major source of HER2 ectodomain sheddase activity in HER2 overexpressing breast cancer cells

Phillip C.C. Liu, Xiangdong Liu, Yanlong Li, +31

Cancer Biology & Therapy

Erbb Family MembersBreast OncologyMolecular BiologyMajor SourceMolecular Research +17

Discovery of Pemigatinib: A Potent and Selective Fibroblast Growth Factor Receptor (FGFR) Inhibitor

Liangxing Wu, Colin Zhang, Chunhong He, +22

Journal of Medicinal Chemistry

INCB38579, a novel and potent histamine H4 receptor small molecule antagonist with anti-inflammatory pain and anti-pruritic functions

Niu Shin, Maryanne Covington, Di Bian, +19

European Journal of Pharmacology

Pain TherapyAnti-inflammatoryPain MedicineMedicineAnti-pruritic Functions +10

Mono- and Bisadducts from the Addition of Thianthrene Cation Radical Salts to Cycloalkenes and Alkenes

Ding‐Quan Qian, Henry J. Shine, I.Y. Guzman-Jimenez, +2

The Journal of Organic Chemistry

Discovery of a Potent, Selective, and Orally Active Human Epidermal Growth Factor Receptor-2 Sheddase Inhibitor for the Treatment of Cancer

Wenqing Yao, Jin‐Cong Zhuo, David Burns, +32

Journal of Medicinal Chemistry

ImmunologySelective InhibitorsPharmacotherapyDermatologyTumor Biology +14

New Strategy for the Synthesis of Phosphonyl Pyrazoles

Hu Chen, Ding‐Quan Qian, Guo‐Xiang Xu, +5

Synthetic Communications

Derivative (Chemistry)4-Phosphonyl Pyrazoles3-Phosphonyl PyrazolesOrganic ChemistrySynthetic Chemistry +6

PREPARATION AND CYCLIZATION OF PHOSPHONYL CHLOROVINYLALDEHYDE

Ding‐Quan Qian, Yuxiu Liu, Ruzhen Cao, +1

Phosphorus, sulfur, and silicon and the related elements

Derivative (Chemistry)EngineeringHeterocyclicNatural SciencesDiversity-oriented Synthesis +8

The Reactions of Hydridophosphorane with Vilsmeier Reagents

Ding‐Quan Qian, Xingzhong Zeng, Xiaodong Shi, +2

Heteroatom Chemistry

Vilsmeier ReagentsBiochemistryExcess 3Natural SciencesHydridophosphorane 3 +6

Ring‐opening reactions of 5‐(aryl)thianthrenium bromides with aryl thiolates

Ding‐Quan Qian, Henry J. Shine, I.Y. Guzman-Jimenez, +1

Journal of Physical Organic Chemistry

Chemical EngineeringSulfuranes 13EngineeringOrganic ChemistryOrganometallic Catalysis +5

Asymmetric Synthesis of Conformationally Constrained <i>trans</i>-2,3-Piperidinedicarboxylic Acid Derivatives

Jin‐Cong Zhuo, Wenqing Yao, David Burns, +10

Synlett

DerivativesEngineeringNatural SciencesDiversity-oriented SynthesisAsymmetric Synthesis +11