Methyl-CpG Binding Domain 1 (MBD1) Interacts with the Suv39h1-HP1 Heterochromatic Complex for DNA Methylation-based Transcriptional Repression

Naoyuki Fujita, Sugiko Watanabe, Takaya Ichimura, +5

Journal of Biological Chemistry

Transcriptional Repression and Heterochromatin Formation by MBD1 and MCAF/AM Family Proteins

Takaya Ichimura, Sugiko Watanabe, Yasuo Sakamoto, +3

Journal of Biological Chemistry

Histone ModificationsModified Histone MoleculeLysine 9Epigenetic ChangeGenetics +19

MCAF Mediates MBD1-Dependent Transcriptional Repression

Naoyuki Fujita, Sugiko Watanabe, Takaya Ichimura, +4

Molecular and Cellular Biology

Histone ModificationsEpigenetic ChangeGeneticsDna MethylationEpigenetics +16

Involvement of SUMO Modification in MBD1- and MCAF1-mediated Heterochromatin Formation

Yasuhiro Uchimura, Takaya Ichimura, Junsuke Uwada, +4

Journal of Biological Chemistry

Nuclear and chromatin reorganization in the MHC-Oct3/4 locus at developmental phases of embryonic stem cell differentiation

Takahiro Aoto, Noriko Saitoh, Takaya Ichimura, +2

Developmental Biology

GeneticsCell DifferentiationStem Cell BiologyChromatin ReorganizationEpigenetics +15

Methylated DNA-binding domain 1 and methylpurine–DNA glycosylase link transcriptional repression and DNA repair in chromatin

Sugiko Watanabe, Takaya Ichimura, Naoyuki Fujita, +5

Proceedings of the National Academy of Sciences

MCAF1/AM Is Involved in Sp1-mediated Maintenance of Cancer-associated Telomerase Activity

Lifeng Liu, Ko Ishihara, Takaya Ichimura, +7

Journal of Biological Chemistry

Overlapping Roles of the Methylated DNA-binding Protein MBD1 and Polycomb Group Proteins in Transcriptional Repression of HOXA Genes and Heterochromatin Foci Formation

Yasuo Sakamoto, Sugiko Watanabe, Takaya Ichimura, +4

Journal of Biological Chemistry

Ascl1-induced Wnt11 regulates neuroendocrine differentiation, cell proliferation, and E-cadherin expression in small-cell lung cancer and Wnt11 regulates small-cell lung cancer biology

Yuki Tenjin, Shinji Kudoh, Sho Kubota, +8

Laboratory Investigation

Tumor BiologyAscl1-induced Wnt11MedicineCancer Cell BiologyCell Proliferation +9

Significance of achaete-scute complex homologue 1 (ASCL1) in pulmonary neuroendocrine carcinomas; RNA sequence analyses using small cell lung cancer cells and Ascl1-induced pulmonary neuroendocrine carcinoma cells

Shinji Kudoh, Yuki Tenjin, Hiroki Kameyama, +6

Histochemistry and Cell Biology

Pulmonary Neuroendocrine CarcinomasTumor BiologyOncogenic AgentMedicinePathology +7