Concepedia

Purakkattle Biju

PB

Statistics

Publications

11

Citations

292

H-Index

11

Active since

1999

Affiliations

Merck & Co., Inc., Rahway, NJ, USA (United States)(Current)

United States Pharmacopeial Convention

Purakkattle Biju is an author at Merck & Co., Inc., Rahway, NJ, USA (United States) specializing in drug discovery, medicine, and pharmacology.

Top concepts

Publications per year

1999–2018

11

Publications

11

Discovery of 2-Hydroxy-<i>N</i>,<i>N</i>-dimethyl-3-{2-[[(<i>R</i>)-1-(5- methylfuran-2-yl)propyl]amino]-3,4-dioxocyclobut-1-enylamino}benzamide (SCH 527123):  A Potent, Orally Bioavailable CXCR2/CXCR1 Receptor Antagonist

Michael P. Dwyer, Younong Yu, Jianping Chao et al. · Journal of Medicinal Chemistry · 2006 · 113 citations · Full text

, , +18

C(4)-alkyl substituted furanyl cyclobutenediones as potent, orally bioavailable CXCR2 and CXCR1 receptor antagonists

Jianhua Chao, Arthur G. Taveras, Jianping Chao et al. · Bioorganic & Medicinal Chemistry Letters · 2007 · 43 citations · Full text

, , +7

3,4-Diamino-2,5-thiadiazole-1-oxides as potent CXCR2/CXCR1 antagonists

Purakkattle Biju, Arthur G. Taveras, Younong Yu et al. · Bioorganic & Medicinal Chemistry Letters · 2007 · 23 citations · Full text

, , +4

Steroidal C-21 mercapto derivatives as dissociated steroids: Discovery of an inhaled dissociated steroid

Purakkattle Biju, Kevin D. McCormick, Robert Aslanian et al. · Bioorganic & Medicinal Chemistry Letters · 2011 · 19 citations · Full text

, , +7

Synthesis and structure–activity relationships of heteroaryl substituted-3,4-diamino-3-cyclobut-3-ene-1,2-dione CXCR2/CXCR1 receptor antagonists

Younong Yu, Michael P. Dwyer, Jianping Chao et al. · Bioorganic & Medicinal Chemistry Letters · 2008 · 17 citations · Full text

, , +6

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