Development of innovative technologies to decrease the environmental burdens associated with using chitin as a biomass resource: Mechanochemical grinding and enzymatic degradation

Yuko Nakagawa, Yasuhiro Oyama, Nobuko Kon, +7

Carbohydrate Polymers

Biomass ConversionEngineeringEnvironmental EngineeringBiomass ResourceBioremediation +3

Hedgehog signaling regulates PDL-1 expression in cancer cells to induce anti-tumor activity by activated lymphocytes

Hideya Onishi, Akiko Fujimura, Yasuhiro Oyama, +6

Cellular Immunology

Cancer ResearchCancer ImmunosurveillanceCell RegulationPdl-1 ExpressionImmunology +10

Patched 1-interacting Peptide Represses Fibrosis in Pancreatic Cancer to Augment the Effectiveness of Immunotherapy

Yasuhiro Oyama, Hideya Onishi, Satoko Koga, +10

Journal of Immunotherapy

ImmunologyImmune RegulationPathologyImmunoeditingImmunotherapeutics +17

FAM115C could be a novel tumor suppressor associated with prolonged survival in pancreatic cancer patients

Kiyoshi Saeki, Hideya Onishi, Satoko Koga, +10

Journal of Cancer

PTPN3 expressed in activated T lymphocytes is a candidate for a non-antibody-type immune checkpoint inhibitor

Akiko Fujimura, Kazunori Nakayama, Akira Imaizumi, +8

Cancer Immunology Immunotherapy

Cancer ImmunosurveillanceAutoimmune DiseaseT-regulatory CellImmune RegulationImmunology +9

Liprin-α4 as a Possible New Therapeutic Target for Pancreatic Cancer

Akio Yamasaki, Kazunori Nakayama, Akira Imaizumi, +6

Anticancer Research

TrkB/BDNF Signaling Could Be a New Therapeutic Target for Pancreatic Cancer

Yasuhiro Oyama, Shinjiro Nagao, Na Lin, +9

Anticancer Research

GLI2 but not GLI1/GLI3 plays a central role in the induction of malignant phenotype of gallbladder cancer

Shu Ichimiya, Hideya Onishi, Shinjiro Nagao, +8

Oncology Reports

Refractory GbcGastroenterologyPathologyCancer BiologyGlioma +19

Protein-bound Polysaccharide-K Inhibits Hedgehog Signaling Through Down-regulation of MAML3 and RBPJ Transcription Under Hypoxia, Suppressing the Malignant Phenotype in Pancreatic Cancer.

Akio Yamasaki, Hideya Onishi, Akira Imaizumi, +4

PubMed

Rbpj TranscriptionImmunologyPathologyCancer BiologyTumor Biology +15

CD24 Modulates Chemosensitivity of MCF-7 Breast Cancer cells

Hideya Onishi, Kumi Suyama, Akio Yamasaki, +4

Anticancer Research