James C. Powers

Human and murine cytotoxic T lymphocyte serine proteases: subsite mapping with peptide thioester substrates and inhibition of enzyme activity and cytolysis by isocoumarins

Shinjiro Odake, Chih Min Kam, Lakshmi Narasimhan et al. · Biochemistry · 1991 · 248 citations

Mechanism-Based Isocoumarin Inhibitors for Human Leukocyte Elastase. Effect of the 7-Amino Substituent and 3-Alkoxy Group in 3-Alkoxy-7-amino-4-chloroisocoumarins on Inhibitory Potency

John E. Kerrigan, Józef Oleksyszyn, Chih-Min Kam et al. · Journal of Medicinal Chemistry · 1995 · 39 citations

Combinatorial Chemistry, Pharmaceutical Science, Bioorganic Chemistry +17

Lymphocyte granule-mediated cytolysis requires serine protease activity

Dorothy Hudig, N.Janine Gregg, Chih-Min Kam et al. · Biochemical and Biophysical Research Communications · 1987 · 38 citations

Protease Inhibitors, Granulocyte, Serine Protease Activity +8

Cutaneous protease activity in the mouse ear vesicant model†

James C. Powers, Chih-Min Kam, Karen M. Ricketts et al. · Journal of Applied Toxicology · 2001 · 32 citations

Allergen, Dermatology, Cellular Physiology +23

[31] Isocoumarin inhibitors of serine peptidases

James C. Powers, C M Kam · Methods in enzymology on CD-ROM/Methods in enzymology · 1994 · 31 citations

Molecular Pharmacology, Medicinal Chemistry, Medicine +7