Conserved structural elements in the V3 crown of HIV-1 gp120

Xunqing Jiang, Valicia Burke, Maxim Totrov, +5

Nature Structural & Molecular Biology

Virus StructureHiv-1 Gp120Natural SciencesHuman RetrovirusAntiviral Response +8

Catalytic activation of multimeric RNase E and RNase G by 5′-monophosphorylated RNA

Xunqing Jiang, Joel G. Belasco

Proceedings of the National Academy of Sciences

Regions of RNase E Important for 5′-End-Dependent RNA Cleavage and Autoregulated Synthesis

Xunqing Jiang, Alexis A. Diwa, Joel G. Belasco

Journal of Bacteriology

Ligand-Specific Opening of a Gated-Porin Channel in the Outer Membrane of Living Bacteria

Xunqing Jiang, Marvin A. Payne, Zhenghua Cao, +4

Science

Iron MetabolismBacteriologyLigand-gated Membrane ChannelsLigand-specific OpeningBacterial Pathogens +16

Cross-Clade HIV-1 Neutralizing Antibodies Induced with V3-Scaffold Protein Immunogens following Priming with gp120 DNA

Susan Zolla‐Pazner, Xiang‐Peng Kong, Xunqing Jiang, +7

Journal of Virology

Double mutagenesis of a positive charge cluster in the ligand-binding site of the ferric enterobactin receptor, FepA

Salete M. Newton, Jennifer S. Allen, Zhenghua Cao, +7

Proceedings of the National Academy of Sciences

Double MutagenesisBiochemistryOuter MembraneLigand-binding SiteCommon Binding Site +12

Human Anti-V3 HIV-1 Monoclonal Antibodies Encoded by the VH5-51/VL Lambda Genes Define a Conserved Antigenic Structure

Miroslaw K. Górny, Jared M. Sampson, Huiguang Li, +11

PLoS ONE

ImmunologyMolecular BiologyAntigen ProcessingViral Structural ProteinImmunotherapy +16

Structure-guided design and immunological characterization of immunogens presenting the HIV-1 gp120 V3 loop on a CTB scaffold

Maxim Totrov, Xunqing Jiang, Xiang‐Peng Kong, +11

Virology

Ctb ScaffoldVirus StructureHuman RetrovirusImmunologyAntiviral Response +9

Multimeric Epitope-Scaffold HIV Vaccines Target V1V2 and Differentially Tune Polyfunctional Antibody Responses

Ann J. Hessell, Rebecca Powell, Xunqing Jiang, +14

Cell Reports

Rationally Designed Vaccines Targeting the V2 Region of HIV-1 gp120 Induce a Focused, Cross-Clade-Reactive, Biologically Functional Antibody Response

Susan Zolla‐Pazner, Rebecca Powell, Sara Yahyaei, +9

Journal of Virology