Synthesis of 1-/2-substituted-[1,2,3]triazolo[4,5-g]phthalazine-4,9-diones and evaluation of their cytotoxicity and topoisomerase II inhibition

Jin Sung Kim, Hee‐Kyung Rhee, Hyen Joo Park, +3

Bioorganic & Medicinal Chemistry

Medicinal ChemistryDerivative (Chemistry)HeterocyclicMedicineOrganic Chemistry +5

Synthesis, cytotoxicity, and DNA topoisomerase II inhibitory activity of benzofuroquinolinediones

Hee‐Kyung Rhee, Hyen Joo Park, Sang Kook Lee, +2

Bioorganic & Medicinal Chemistry

BiochemistryMedicineAnti-cancer AgentDrug DevelopmentPharmacology +3

Synthesis and evaluation of benzoxazole derivatives as 5-lipoxygenase inhibitors

Hyunmin Song, Sei‐Ryang Oh, Hyeong‐Kyu Lee, +6

Bioorganic & Medicinal Chemistry

Medicinal ChemistryDerivative (Chemistry)BiochemistryMedicineNatural Sciences +4

Synthesis of 6-chloroisoquinoline-5,8-diones and pyrido[3,4-b]phenazine-5,12-diones and evaluation of their cytotoxicity and DNA topoisomerase II inhibitory activity

Jin Sung Kim, Hee‐Kyung Rhee, Hyen Joo Park, +6

Bioorganic & Medicinal Chemistry

Medicinal ChemistryBioorganic ChemistryHeterocyclicBiochemistryNatural Sciences +6

Synthesis and cytotoxicity of 2-phenylquinazolin-4(3H)-one derivatives

Hee‐Kyung Rhee, Ji Hye Yoo, Eun‐Young Lee, +4

European Journal of Medicinal Chemistry

Derivative (Chemistry)DerivativesOrganic ChemistryHeterocycle ChemistryPharmacology +1

Synthesis and cytotoxicity evaluation of substituted pyridazino[4,5-b]phenazine-5,12-diones and tri/tetra-azabenzofluorene-5,6-diones

Hyun‐Jung Lee, Jin Sung Kim, Myung-Eun Suh, +8

European Journal of Medicinal Chemistry

HeterocyclicOrganic ChemistryChemistryHeterocycle ChemistryPharmacology +2

Synthesis of isoquinolinone-based tetracycles as poly (ADP-ribose) polymerase-1 (PARP-1) inhibitors

Hee‐Kyung Rhee, So Yun Lim, Mi-Ja Jung, +3

Bioorganic & Medicinal Chemistry

Bioorganic ChemistryBiochemistryNatural SciencesMedicineOrganic Chemistry +6

Synthesis and T-type calcium channel blocking activity of novel diphenylpiperazine compounds, and evaluation of in vivo analgesic activity

Yoo Lim Kam, Hee‐Kyung Rhee, Hyewhon Rhim, +3

Bioorganic & Medicinal Chemistry

Medicinal ChemistryMedicineVivo Analgesic ActivityAnesthetic MechanismNovel Diphenylpiperazine Compounds +8

Synthesis, Cytotoxicity and Topoisomerase II Inhibitory Activity of Benzonaphthofurandiones

Hee‐Kyung Rhee, Youngjoo Kwon, Hwa‐Jin Chung, +2

Bulletin of the Korean Chemical Society

Medicinal ChemistryBioorganic ChemistryBiochemistryNatural SciencesMedicine +9

Pharmacokinetics of propentofylline and the quantitation of its metabolite hydroxypropentofylline in human volunteers

Oh‐Seung Kwon, Youn‐Bok Chung, Min-Hee Kim, +3

Archives of Pharmacal Research

Drug AnalysisPharmacological StudyBiochemistryHuman VolunteersPharmacology +5