CD28-dependent Rac1 activation is the molecular target of azathioprine in primary human CD4+ T lymphocytes

Imke Tiede, Gerhard Fritz, Susanne Strand, +17

Journal of Clinical Investigation

Human thiopurine methyltransferase pharmacogenetics: Gene sequence polymorphisms*

Diane M. Otterness, Carol L. Szumlanski, Lynne Lennard, +8

Clinical Pharmacology & Therapeutics

Allelic VariantGenetic DeterminantAllergyMedicineGenetics +12

CD28-dependent Rac1 activation is the molecular target of azathioprine in primary human CD4+ T lymphocytes

Imke Tiede, Gerhard Fritz, Susanne Strand, +17

Journal of Clinical Investigation

Clinical ImmunologyApoptosisImmunologyImmune RegulationCell Death +24

Thiopurine S -methyltransferase activity in human erythrocytes: a new HPLC method using 6-thioguanine as substrate

T. Kröplin, N. Weyer, Sven Gutsche, +1

European Journal of Clinical Pharmacology

BiochemistryMedicineBioanalysisHematologyHuman Erythrocytes +3

Influence of continuous veno–venous haemodiafiltration and continuous veno–venous haemofiltration on the pharmacokinetics of fluconazole

E Muhl, Timothy P. Martens, H. Iven, +2

European Journal of Clinical Pharmacology

PharmacologyPharmacotherapyContinuous Veno–venous HaemodiafiltrationContinuous Veno–venous HaemofiltrationMedicine +1

Pharmacokinetics of Levofloxacin During Continuous Venovenous Hemodiafiltration and Continuous Venovenous Hemofiltration in Critically Ill Patients

Sven G. Guenter, H. Iven, Carsten Boos, +2

Pharmacotherapy The Journal of Human Pharmacology and Drug Therapy

Pharmacokinetics in the rat of the hallucinogenic alkaloids harmine and harmaline

G. Zetler, G. Back, H. Iven

Naunyn-Schmiedeberg s Archives of Pharmacology

Psychoactive DrugPharmacological StudyMedicinePhysiologyToxicology +5

The pathophysiological profile of the acute cardiovascular toxicity of sodium fluoride

O. Strubelt, H. Iven, Maged Younes

Toxicology

Heart FailureCardiovascular DiseaseSodium HomeostasisMedicinePhysiology +6

Human thiopurine S-methyltransferase activity in uremia and after renal transplantation

N. Weyer, T. Kröplin, Lutz Fricke, +1

European Journal of Clinical Pharmacology

UrologyTransplantationKidney TransplantKidney TransplantationChronic Kidney Disease +6

Influence of the antibiotics piperacillin, doxycycline, and tobramycin on the pharmacokinetics of methotrexate in rabbits

H. Iven, Helmut Brasch

Cancer Chemotherapy and Pharmacology

Antibiotics PiperacillinPharmacological StudyAntibioticsMedicinePharmacotherapy +5