Cellular basis for defective electrolyte transport in inflamed human colon

Geoffrey I. Sandle, N. B. Higgs, Peter T. Crowe, +3

Gastroenterology

Cell PhysiologyDefective Electrolyte TransportMembrane TransportPhysiologyCell Trafficking +6

Modulation of the Permeability of H2 Receptor Antagonists Cimetidine and Ranitidine by P-Glycoprotein in Rat Intestine and the Human Colonic Cell Line Caco-2

Andrew Collett, N. B. Higgs, Erika Sims, +2

Journal of Pharmacology and Experimental Therapeutics

Region-Dependent Modulation of Intestinal Permeability by Drug Efflux Transporters: In Vitro Studies in mdr1a(−/−) Mouse Intestine

R. Stephens, Jolanta Tanianis-Hughes, N. B. Higgs, +2

Journal of Pharmacology and Experimental Therapeutics

Loperamide has antisecretory activity in the human jejunum in vivo.

Sarah Jane Hughes, N. B. Higgs, L A Turnberg

Gut

MedicinePathogenesisPhysiologyGastroenterologyAffect Net Absorption +11

Somatostatin receptor subtype 2 mediates somatostatin inhibition of ion secretion in rat distal colon

G. Warhurst, N. B. Higgs, Hana Fakhoury, +3

Gastroenterology

InflammationSignal TransductionGastrointestinal PharmacologyMedicinePhysiology +8

Antidiarrhoeal activity of loperamide: studies of its influence on ion transport across rabbit ileal mucosa in vitro.

Sarah Jane Hughes, N. B. Higgs, L A Turnberg

Gut

Rabbit Ileal MucosaIon TransportProstaglandin E2Health SciencesGastrointestinal Pharmacology +13

Influence of atrial natriuretic peptide on mammalian large intestine

Kieran Moriarty, N. B. Higgs, Michael Lees, +3

Gastroenterology

CardiologyPhysiologyGastrointestinal Peptide HormoneAtrial Natriuretic Peptide

Studies of the antisecretory activity of morphine in rabbit ileum in vitro

J McKay, B D Linaker, N. B. Higgs, +1

Gastroenterology

Rabbit IleumGastrointestinal PharmacologyMedicineGastroenterologyExperimental Pharmacology +4

Multiple G-protein-dependent pathways mediate the antisecretory effects of somatostatin and clonidine in the HT29-19A colonic cell line.

G. Warhurst, L.A. Turnberg, N. B. Higgs, +3

Journal of Clinical Investigation

Protein SecretionGastrointestinal PharmacologyImmunologyGastroenterologyAntisecretory Effects +17

Mechanisms of histamine stimulated secretion in rabbit ileal mucosa.

B D Linaker, J McKay, N. B. Higgs, +1

Gut