The cholesterol metabolite 27 hydroxycholesterol facilitates breast cancer metastasis through its actions on immune cells

Amy E. Baek, Yen-Rei A. Yu, Sisi He, +12

Nature Communications

CaMKK2 in myeloid cells is a key regulator of the immune-suppressive microenvironment in breast cancer

Luigi Racioppi, Erik R. Nelson, Wei Huang, +19

Nature Communications

27-Hydroxycholesterol acts on myeloid immune cells to induce T cell dysfunction, promoting breast cancer progression

Liqian Ma, Lawrence Wang, Adam Nelson, +12

Cancer Letters

Cancer ImmunosurveillanceT Cell DysfunctionMedicineT-regulatory CellImmunology +8

cAMP/CREB-mediated Transcriptional Regulation of Ectonucleoside Triphosphate Diphosphohydrolase 1 (CD39) Expression

Hui Liao, Matthew C. Hyman, Amy E. Baek, +2

Journal of Biological Chemistry

Molecular RegulationCamp/creb-mediated Transcriptional RegulationMolecular BiologyCd39 PromoterCellular Physiology +23

Host CYP27A1 expression is essential for ovarian cancer progression

Sisi He, Liqian Ma, Amy E. Baek, +6

Endocrine Related Cancer

Cancer MetabolismImmune CheckpointOxysterolMedicinePharmacology +9

Flow-dependent expression of ectonucleotide tri(di)phosphohydrolase-1 and suppression of atherosclerosis

Yogendra Kanthi, Matthew C. Hyman, Hui Liao, +7

Journal of Clinical Investigation

Ovalbumin sensitization and challenge increases the number of lung cells possessing a mesenchymal stromal cell phenotype

J. Kelley Bentley, Antonia P. Popova, Paul D. Bozyk, +5

Respiratory Research

The Cholesterol Metabolite 27HC Increases Secretion of Extracellular Vesicles Which Promote Breast Cancer Progression

Amy E. Baek, Natalia Krawczyńska, Anasuya Das Gupta, +16

Endocrinology

Ischemic Cerebroprotection Conferred by Myeloid Lineage-Restricted or Global CD39 Transgene Expression

Amy E. Baek, Nadia R. Sutton, Danica Petrovic‐Djergovic, +5

Circulation

Regulation of ecto‐apyrase CD39 (ENTPD1) expression by phosphodiesterase III (PDE3)

Amy E. Baek, Yogendra Kanthi, Nadia R. Sutton, +2

The FASEB Journal

ImmunologyMolecular BiologyCd39 ProteinInflammationThrombosis +15