Deferasirox is a powerful NF- B inhibitor in myelodysplastic cells and in leukemia cell lines acting independently from cell iron deprivation by chelation and reactive oxygen species scavenging

Emanuela Messa, Sonia Carturan, Chiara Maffè, +14

Haematologica

The NF-κB pathway blockade by the IKK inhibitor PS1145 can overcome Imatinib resistance

Daniela Cilloni, F. Messa, Francesca Arruga, +12

Leukemia

Imatinib ResistanceMedicineImmunologyImmune Checkpoint InhibitorNf-κb Pathway Blockade +5

Imatinib and pegylated human recombinant interferon-α2b in early chronic-phase chronic myeloid leukemia

Michele Baccarani, Giovanni Martinelli, Gianantonio Rosti, +19

Blood

Deferasirox Treatment Improved the Hemoglobin Level and Decreased Transfusion Requirements in Four Patients with the Myelodysplastic Syndrome and Primary Myelofibrosis

Emanuela Messa, Daniela Cilloni, F. Messa, +3

Acta Haematologica

Increase in platelet count in older, poor‐risk patients with acute myeloid leukemia or myelodysplastic syndrome treated with valproic acid and all‐trans retinoic acid

Chiara Pilatrino, Daniela Cilloni, Emanuela Messa, +9

Cancer

Early prediction of treatment outcome in acute myeloid leukemia by measurement of WT1 transcript levels in peripheral blood samples collected after chemotherapy

Daniela Cilloni, F. Messa, Francesca Arruga, +13

Haematologica

Increase sensitivity to chemotherapeutical agents and cytoplasmatic interaction between NPM leukemic mutant and NF-κB in AML carrying NPM1 mutations

Daniela Cilloni, F. Messa, Valentina Rosso, +13

Leukemia

Hematological MalignancyMedicineImmunologyNpm1 MutationsIncrease Sensitivity +6

Sensitivity to imatinib therapy may be predicted by testing Wilms tumor gene expression and colony growth after a short in vitro incubation

Daniela Cilloni, Francesca Messa, Enrico Gottardi, +11

Cancer

Core binding factor acute myeloid leukaemia and c-KIT mutations

Ludovica Riera, Filippo Marmont, DANIELA TOPPINO, +10

Oncology Reports

Down-modulation of the C/EBPα transcription factor in core binding factor acute myeloid leukemias

Daniela Cilloni, Sonia Carturan, Enrico Gottardi, +7

Blood