J.L. Chuang

Molecular Phenotypes in Cultured Maple Syrup Urine Disease Cells

C. Fisher, J.L. Chuang, T A Griffin et al. · Journal of Biological Chemistry · 1989 · 68 citations · Full text

Life Sciences, Molecular Biology, Molecular Genetics +12

Isolation and sequencing of a cDNA encoding the decarboxylase (E1)alpha precursor of bovine branched-chain alpha-keto acid dehydrogenase complex. Expression of E1 alpha mRNA and subunit in maple-syrup-urine-disease and 3T3-L1 cells.

C W Hu, Kim S. Lau, T A Griffin et al. · Journal of Biological Chemistry · 1988 · 46 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +15

Maple syrup urine disease in Mennonites. Evidence that the Y393N mutation in E1 alpha impedes assembly of the E1 component of branched-chain alpha-keto acid dehydrogenase complex.

Carolyn R. Fisher, J.L. Chuang, R. P. Cox et al. · Journal of Clinical Investigation · 1991 · 43 citations · Full text

Life Sciences, Genetics, Molecular Genetics +13

Cloning and expression in Escherichia coli of mature E1 beta subunit of bovine mitochondrial branched-chain alpha-keto acid dehydrogenase complex. Mapping of the E1 beta-binding region on E2.

Richard Wynn, J.L. Chuang, James Davie et al. · Journal of Biological Chemistry · 1992 · 34 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +13

Molecular and biochemical basis of intermediate maple syrup urine disease. Occurrence of homozygous G245R and F364C mutations at the E1 alpha locus of Hispanic-Mexican patients.

J.L. Chuang, James Davie, Jeffrey M. Chinsky et al. · Journal of Clinical Investigation · 1995 · 34 citations · Full text

Life Sciences, Biochemistry, Genetics +17