Importance of hepatic metabolism in the antiaggregating activity of the thienopyridine clopidogrel

Pierre Savi, Jean‐Marc Herbert, A. M. Pflieger, +5

Biochemical Pharmacology

BiochemistryMedicineLiver PhysiologyPhysiologyHepatic Metabolism +9

DX 9065A a novel, synthetic, selective and orally active inhibitor of factor Xa: in vitro and in vivo studies.

Jean‐Marc Herbert, A. Bernat, F. Dol, +3

Journal of Pharmacology and Experimental Therapeutics

IL‐4 and IL‐13 exhibit comparable abilities to reduce pyrogen‐induced expression of procoagulant activity in endothelial cells and monocytes

Jean‐Marc Herbert, Pierre Savi, M.-Cl. Laplace, +5

FEBS Letters

Induction of vascular smooth muscle cell growth by selective activation of the thrombin receptor Effect of heparin

Jean‐Marc Herbert, Isabelle Lamarche, F. Dol

FEBS Letters

Selective ActivationCellular PhysiologyThrombosisAngiogenesisSynthetic Peptide +21

Tissue-type plasminogen activator is a potent mitogen for human aortic smooth muscle cells.

Jean‐Marc Herbert, Isabelle Lamarche, V. Prabonnaud, +2

Journal of Biological Chemistry

Muscle FunctionVascular CompromiseCardiovascular FunctionCellular PhysiologyAngiogenesis +18

Effector protease receptor 1 mediates the mitogenic activity of factor Xa for vascular smooth muscle cells in vitro and in vivo.

Jean‐Marc Herbert, Françoise Bono, J. Hérault, +4

Journal of Clinical Investigation

Mitogenic ActivityImmunologyCytoskeletonFactor XCellular Physiology +15

Effect of Clopidogrel on Thrombin Generation in Platelet-Rich Plasma in the Rat

Jean-P. Hérault, F. Dol, C Gaich, +2

Thrombosis and Haemostasis

Thrombin Peak ConcentrationPharmacotherapyAdp-induced Platelet AggregationInflammationThrombosis +15

Effect of SR-49059, a vasopressin V1a antagonist, on human vascular smooth muscle cells

C. Serradeil‐Le Gal, Jean‐Marc Herbert, Chantal Delisée, +7

American Journal of Physiology-Heart and Circulatory Physiology

HypertensionImmunologyCardiovascular FunctionVasopressin V1a AntagonistCellular Physiology +15

A Simple Method to Measure Dermatan Sulfate at Sub-Microgram Concentrations in Plasma

D. Dupouy, Piérre Siè, F. Dol, +1

Thrombosis and Haemostasis

Effects of increased sulfation of dermatan sulfate on its in vitro and in vivo pharmacological properties

F. Dol, C. Caranobe, D. Dupouy, +5

Thrombosis Research

BiochemistryVivo Pharmacological PropertiesMedicineDermatan SulfateDermatology +3