Concepedia
Author
Michael F. Dunn
Also Known As
8
Publications
522
Citations
H-Index
0
Concepts
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The tryptophan synthase bienzyme complex transfers indole between the .alpha.- and .beta.-sites via a 25-30 .ANG. long tunnel
Michael F. Dunn, Valentin Aguilar, Peter S. Brzović, +4
Biochemistry
1990
167
Reaction mechanism of Escherichia coli cystathionine .gamma.-synthase: direct evidence for a pyridoxamine derivative of vinylgloxylate as a key intermediate in pyridoxal phosphate dependent .gamma.-elimination and .gamma.-replacement reactions
Peter S. Brzović, Elizabeth L. Holbrook, Ronald C. Greene, +1
87
Mechanisms of Stabilization of the Insulin Hexamer through Allosteric Ligand Interactions
Sophie Rahuel-Clermont, Cherie A. French, Niels C. Kaarsholm, +1
1997
85
Substitution of glutamic acid 109 by aspartic acid alters the substrate specificity and catalytic activity of the .beta.-subunit in the tryptophan synthase bienzyme complex from Salmonella typhimurium
Peter S. Brzović, Arvind M. Kayastha, Edith Wilson Miles, +1
1992
55
Proton fourier transform NMR studies of insulin: coordination of calcium to the Glu(B13) site drives hexamer assembly and induces a conformation change
Richard H. Palmieri, Robert W. K. Lee, Michael F. Dunn
1988
42
Allosteric linkages between .beta.-site covalent transformations and .alpha.-site activation and deactivation in the tryptophan synthase bienzyme complex
Catherine A. Leja, Eilika U. Woehl, Michael F. Dunn
1995
39
Mechanism of binding of substrate analogs to tryptophan indole-lyase: studies using rapid-scanning and single-wavelength stopped-flow spectrophotometry
Robert S. Phillips, S. L. BENDER, Peter S. Brzović, +1
31
Spectroscopic evidence for preexisting T- and R-state insulin hexamer conformations
Wonjae E. Choi, Dan Borchardt, Niels C. Kaarsholm, +2
Proteins Structure Function and Bioinformatics
1996
16
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