The Amyloid Precursor Protein of Alzheimer's Disease in the Reduction of Copper(II) to Copper(I)

Gerd Multhaup, Andrea Schlicksupp, Lars Hesse, +4

Science

Neurochemical BiomarkersChemistryAmyloid Precursor ProteinRedox BiologyOxidative Stress +15

The βA4 amyloid precursor protein binding to copper

Lars Hesse, Dirk Beher, Colin L. Masters, +1

FEBS Letters

Crystal structure of the N-terminal, growth factor-like domain of Alzheimer amyloid precursor protein.

Michael W. Parker, Jamie Rossjohn, Roberto Cappai, +8

Nature Structural Biology

Crystal StructureNeurodegenerative DiseasesAlzheimer's DiseaseBiochemistryProtein Assembly +9

Homodimerization of Amyloid Precursor Protein and Its Implication in the Amyloidogenic Pathway of Alzheimer's Disease

Stefan Scheuermann, Boris Hambsch, Lars Hesse, +6

Journal of Biological Chemistry

Protein AssemblyMolecular BiologyNeurochemical BiomarkersCytoskeletonAmyloid Precursor Protein +19

Regulation of Amyloid Protein Precursor (APP) Binding to Collagen and Mapping of the Binding Sites on APP and Collagen Type I

Dirk Beher, Lars Hesse, Colin L. Masters, +1

Journal of Biological Chemistry

Exploiting current understanding of antibiotic action for discovery of new drugs

I. Chopra, Lars Hesse, Alex J. O’Neill

Journal of Applied Microbiology

Copper-Binding Amyloid Precursor Protein Undergoes a Site-Specific Fragmentation in the Reduction of Hydrogen Peroxide

Gerd Multhaup, Thomas Ruppert, Andrea Schlicksupp, +5

Biochemistry

Survival of cultured neurons from amyloid precursor protein knock-out mice against Alzheimer's amyloid-beta toxicity and oxidative stress.

Anthony R. White, Hui Zheng, D Galatis, +6

PubMed

Cultured NeuronsNeurodegenerative DiseasesAlzheimer's DiseaseMolecular NeuroscienceDegenerative Pathology +12

Survival of Cultured Neurons from Amyloid Precursor Protein Knock-Out Mice against Alzheimer’s Amyloid-β Toxicity and Oxidative Stress

Anthony R. White, Hui Zheng, Denise Galatis, +6

Journal of Neuroscience

Cultured NeuronsBrain DevelopmentSynaptic TransmissionAmyloid Precursor ProteinSynaptic Signaling +17

Human Amyloid Precursor‐Like Protein 1

Krzysztof Paliga, Gisela Peraus, Sylvia Kreger, +6

European Journal of Biochemistry