Jean-Yves Leroux

Cellular immunity to the G1 domain of cartilage proteoglycan aggrecan is enhanced in patients with rheumatoid arthritis but only after removal of keratan sulfate

Alexei Guerassimov, Yiping Zhang, Subhashis Banerjee et al. · Arthritis & Rheumatism · 1998 · 68 citations

Medicine, Clinical Sciences, Immunology +17

Immunity to the G1 globular domain of the cartilage proteoglycan aggrecan can induce inflammatory erosive polyarthritis and spondylitis in BALB/c mice but immunity to G1 is inhibited by covalently bound keratan sulfate in vitro and in vivo.

Jean-Yves Leroux, Alexei Guerassimov, Annie Cartman et al. · Journal of Clinical Investigation · 1996 · 65 citations · Full text

Medicine, Immunology, Pathology +16

Arthritis induced by proteoglycan aggrecan G1 domain in BALB/c mice. Evidence for t cell involvement and the immunosuppressive influence of keratan sulfate on recognition of t and b cell epitopes.

Y Zhang, Alexei Guerassimov, Jean-Yves Leroux et al. · Journal of Clinical Investigation · 1998 · 64 citations · Full text

Medicine, Immunology, Pathology +17

Induction of Arthritis in BALB/c Mice by Cartilage Link Protein

Yiping Zhang, Alexei Guerassimov, Jean-Yves Leroux et al. · American Journal Of Pathology · 1998 · 55 citations · Full text

Medicine, Immunology, Molecular Biology +13

Induction, by adriamycin and mitomycin C, of modifications in lipid composition, size distribution, membrane fluidity and permeability of cultured RDM4 lymphoma cells

D. Oth, M.E. Bégin, Philip Bischoff et al. · Biochimica et Biophysica Acta (BBA) - Biomembranes · 1987 · 24 citations

Life Sciences, Biochemistry, Cell Biology +16