Jean‐Michel Luccarini

The new‐generation pan‐peroxisome proliferator‐activated receptor agonist IVA337 protects the liver from metabolic disorders and fibrosis

Guillaume Wettstein, Jean‐Michel Luccarini, Laurence Poekes et al. · Hepatology Communications · 2017 · 128 citations · Full text

Design, Synthesis, and Evaluation of a Novel Series of Indole Sulfonamide Peroxisome Proliferator Activated Receptor (PPAR) α/γ/δ Triple Activators: Discovery of Lanifibranor, a New Antifibrotic Clinical Candidate

Benaı̈ssa Boubia, Olivia Poupardin, Martine Barth et al. · Journal of Medicinal Chemistry · 2018 · 106 citations · Full text

Pharmaceutical Science, Pharmacotherapy, Pharmaceutical Chemistry +19

Pan PPAR agonist IVA337 is effective in prevention and treatment of experimental skin fibrosis

Nadira Ruzehaji, C. Frantz, Matthieu Ponsoye et al. · Annals of the Rheumatic Diseases · 2016 · 92 citations · Full text

Pan-PPAR agonist IVA337 is effective in experimental lung fibrosis and pulmonary hypertension

Jérôme Avouac, Irena Konstantinova, Christophe Guignabert et al. · Annals of the Rheumatic Diseases · 2017 · 80 citations

Design and Synthesis of Potent Bradykinin Agonists Containing a Benzothiazepine Moiety

Muriel Amblard, Isabelle Daffix, Philippe Bedos et al. · Journal of Medicinal Chemistry · 1999 · 62 citations · Full text

Combinatorial Chemistry, Organic Chemistry, Pharmacotherapy +20