S-glutathionylation uncouples eNOS and regulates its cellular and vascular function

Chun‐An Chen, Tse-Yao Wang, Saradhadevi Varadharaj, +6

Nature

InflammationMolecular PhysiologySignal TransductionLipid PeroxidationEndothelial Dysfunction +9

Mitochondrial Complex II in the Post-ischemic Heart

Yeong-Renn Chen, Chwen-Lih Chen, Douglas R. Pfeiffer, +1

Journal of Biological Chemistry

Phosphorylation of Endothelial Nitric-oxide Synthase Regulates Superoxide Generation from the Enzyme

Chun‐An Chen, Lawrence J. Druhan, Saradhadevi Varadharaj, +2

Journal of Biological Chemistry

Nitric OxideRedox BiologyCellular PhysiologyOxidative StressInflammation +16

Superoxide Generation from Mitochondrial NADH Dehydrogenase Induces Self-inactivation with Specific Protein Radical Formation

Yeong-Renn Chen, Chwen-Lih Chen, Liwen Zhang, +2

Journal of Biological Chemistry

Reductive StressRedox SignalingSuperoxide GenerationMitochondrial FunctionBiochemistry +12

Endothelium-Derived Nitric Oxide Regulates Postischemic Myocardial Oxygenation and Oxygen Consumption by Modulation of Mitochondrial Electron Transport

Xue Zhao, Guanglong He, Yeong-Renn Chen, +3

Circulation

Proteomic analysis of protein tyrosine nitration after ischemia reperfusion injury: Mitochondria as the major target

Bin Liu, Arun K. Tewari, Liwen Zhang, +4

Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics

BiochemistryMitochondrial FunctionMedicineNatural SciencesReperfusion Injury +10

Peroxynitrite Induces Destruction of the Tetrahydrobiopterin and Heme in Endothelial Nitric Oxide Synthase: Transition from Reversible to Irreversible Enzyme Inhibition

Weiguo Chen, Lawrence J. Druhan, Chun‐An Chen, +5

Biochemistry

Peroxynitrite Induces DestructionRedox BiologyOxidative StressInflammationReactive Nitrogen Specie +15

Biphasic modulation of the mitochondrial electron transport chain in myocardial ischemia and reperfusion

Hsin-Ling Lee, Chwen-Lih Chen, Steve T. Yeh, +2

American Journal of Physiology-Heart and Circulatory Physiology

Myocardial IschemiaCardiac MuscleMitochondrial BiologyRedox BiologyOxidative Stress +17

Characterization of the Mechanism of Cytochrome P450 Reductase-Cytochrome P450-mediated Nitric Oxide and Nitrosothiol Generation from Organic Nitrates

Haitao Li, Xiaoping Liu, Hongmei Cui, +3

Journal of Biological Chemistry

Site-Specific S-Glutathiolation of Mitochondrial NADH Ubiquinone Reductase

Chwen-Lih Chen, Liwen Zhang, Alexander Yeh, +4

Biochemistry