A common protein fold and similar active site in two distinct families of β-glycanases

Roberto Domínguez, Hélène Souchon, Silvia Spinelli, +5

Nature Structural Biology

Protein GlycosylationProtein AssemblyBiochemistryProtein FoldingCommon Protein Fold +9

Three-dimensional structures of the free and the antigen-complexed Fab from monoclonal anti-lysozyme antibody D44.1

Bradford C. Braden, Hélène Souchon, Jean-Luc Eiselé, +4

Journal of Molecular Biology

ImmunologyMolecular BiologyAntigen-complexed FabImmunochemistryAntibody Engineering +6

Atomic (0.94 Å) resolution structure of an inverting glycosidase in complex with substrate

Diego M. A. Guérin, Marie‐Bernard Lascombe, Marcelo D. Costabel, +4

Journal of Molecular Biology

BiochemistryNatural SciencesGlycobiologyProtein X-ray CrystallographyMolecular Biology +8

Use of site-directed mutagenesis to probe the structure, function and isoniazid activation of the catalase/peroxidase, KatG, from Mycobacterium tuberculosis

Brigitte Saint‐Joanis, Hélène Souchon, Martin Wilming, +3

Biochemical Journal

Bioorganic ChemistryAldo-keto ReductaseUnstable EnzymeEnzymatic ModificationRedox Biology +16

The Crystal Structure and Catalytic Mechanism of Cellobiohydrolase CelS, the Major Enzymatic Component of the Clostridium thermocellum Cellulosome

B.G. Guimarães, Hélène Souchon, Betsy L. Lytle, +2

Journal of Molecular Biology

Crystal StructureBiosynthesisCellular EnzymologyBiochemistryNatural Sciences +6

Structure and Mechanism of the Alkyl Hydroperoxidase AhpC, a Key Elementof the Mycobacterium tuberculosis Defense System against OxidativeStress

B.G. Guimarães, Hélène Souchon, Nadine Honoré, +5

Journal of Biological Chemistry

Crystal StructureAlkyl Hydroperoxidase AhpcKey ElementofMolecular BiologyChemical Biology +14

The Crystal Structure of a Family 5 Endoglucanase Mutant in Complexed and Uncomplexed Forms Reveals an Induced Fit Activation Mechanism

Hélène Souchon, Marie‐Bernard Lascombe, Pedro M. Alzari

Journal of Molecular Biology

Crystal StructureBiochemistryProtein AssemblyProtein FoldingEndoglucanase Mutant +11

Crystal Structure of a Cross-reaction Complex between Fab F9.13.7 and Guinea Fowl Lysozyme

Julien Lescar, Matteo Pellegrini, Hélène Souchon, +5

Journal of Biological Chemistry

Structural and Functional Analysis of the Metal-binding Sites of Clostridium thermocellum Endoglucanase CelD

Sylvie Chauvaux, Hélène Souchon, Pedro M. Alzari, +2

Journal of Biological Chemistry

Use of site-directed mutagenesis to probe the structure, function and isoniazid activation of the catalase/peroxidase, KatG, from Mycobacterium tuberculosis

Brigitte Saint‐Joanis, Hélène Souchon, Martin Wilming, +3

Biochemical Journal

Bioorganic ChemistryAldo-keto ReductaseUnstable EnzymeEnzymatic ModificationRedox Biology +16