Alexander Hegmans - Concepedia

Author

Alexander Hegmans

Virginia Commonwealth University

Also Known As

Alexander Hegmans, Hegmans, A., Hegmans, Alexander

Publications

548

Citations

H-Index

Concepts

All Affiliations

Virginia Commonwealth University TU Dortmund University University of Trieste The University of Western Australia

About

Alexander Hegmans is an author at Virginia Commonwealth University specializing in natural sciences, molecular biology, and biochemistry.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Natural Sciences	9	9	291
2	Biochemistry	6	6	155
3	Engineering	3	3	64
4	Medicine	3	3	119
5	Biomolecular Engineering	3	3	68

Alexander Hegmans

Publications

542

Citations

H-Index

Page 1

	Year	Citations
Long Range 1,4 and 1,6-Interstrand Cross-Links Formed by a Trinuclear Platinum Complex. Minor Groove Preassociation Affects Kinetics and Mechanism of Cross-Link Formation as Well as Adduct Structure Alexander Hegmans, Susan J. Berners‐Price, Murray S. Davies, Journal of the American Chemical Society	2004	106
Kinetic and Equilibria Studies of the Aquation of the Trinuclear Platinum Phase II Anticancer Agent [{<i>trans</i>-PtCl(NH<sub>3</sub>)<sub>2</sub>}<sub>2</sub>{μ-<i>trans</i>-Pt(NH<sub>3</sub>)<sub>2</sub>(NH<sub>2</sub>(CH<sub>2</sub>)<sub>6</sub>NH<sub>2</sub>)<sub>2</sub>}]<sup>4+</sup> (BBR3464) Murray S. Davies, Donald S. Thomas, Alexander Hegmans, Inorganic Chemistry	2002	71
A comparison of DNA binding profiles of dinuclear platinum compounds with polyamine linkers and the trinuclear platinum phase II clinical agent BBR3464 Tracey D. McGregor, Alexander Hegmans, Jana Kašpárková, JBIC Journal of Biological Inorganic Chemistry ChromatinPolyamine LinkersNucleic Acid ChemistryMedicineNatural Sciences	2002	59
Synthesis and DNA conformational changes of non-covalent polynuclear platinum complexes Yun Qu, Amanda L. Harris, Alexander Hegmans, Journal of Inorganic Biochemistry Inorganic ChemistryDna Conformational ChangesNatural SciencesCoordination ComplexMolecular Biology	2004	47
Novel Approaches to Polynuclear Platinum Pro-Drugs. Selective Release of Cytotoxic Platinum−Spermidine Species through Hydrolytic Cleavage of Carbamates Alexander Hegmans, Yun Qu, Lloyd R. Kèlland, Inorganic Chemistry	2001	39
Pt as Mediator of Strong Antiferromagnetic Coupling between Two CuII Ions in a Heteronuclear CuIIPtIICuII Complex of the Model Nucleobase 1-Methylcytosinate Alexander Hegmans, Ennio Zangrando, E. Freisinger, Chemistry - A European Journal Molecular BiologyTrinuclear Cuiiptcuii ComplexesChemistryInorganic CompoundHeteronuclear Cuiiptiicuii Complex	1999	31
Amide-Based Prodrugs of Spermidine-Bridged Dinuclear Platinum. Synthesis, DNA Binding, and Biological Activity Alexander Hegmans, Jana Kašpárková, Oldřich Vrána, Journal of Medicinal Chemistry Medicinal ChemistryAmide-based ProdrugsDna BindingPharmaceutical ScienceBiochemistry	2008	30
The phosphate clamp as recognition motif in platinum–DNA interactions Seiji Komeda, Yun Qu, John B. Mangrum, Inorganica Chimica Acta ChromatinNucleic Acid ChemistryPhosphate ClampNatural SciencesDna Analysis	2016	30
Effects of geometric isomerism in dinuclear antitumor platinum complexes on their interactions with N-acetyl-L-methionine Michael E. Oehlsen, Alexander Hegmans, Yun Qu, JBIC Journal of Biological Inorganic Chemistry Inorganic ChemistryMedicinal ChemistryGeometric IsomerismBiochemistryNatural Sciences	2005	29
Synthetic Ways to Tris(nucleobase) Complexes Derived from <i>cis</i>-Diammineplatinum(II) and a Platinum(II) Complex Containing Four Different Ligands, Three of Which Are Nucleobases Alexander Hegmans, Michal Sabat, Ivan Baxter, Inorganic Chemistry Inorganic ChemistryEngineeringBiochemistryComplexes DerivedNatural Sciences	1998	27

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