Concepedia

Alexander Hegmans

AH

14

Publications

542

Citations

12

H-Index

1998

Active since

Affiliations

Virginia Commonwealth University(Current)

TU Dortmund University

University of Trieste

The University of Western Australia

Alexander Hegmans is an author at Virginia Commonwealth University specializing in natural sciences, molecular biology, and biochemistry.

Top concepts

Publications per year

1998–2016

14

Publications

14

Long Range 1,4 and 1,6-Interstrand Cross-Links Formed by a Trinuclear Platinum Complex. Minor Groove Preassociation Affects Kinetics and Mechanism of Cross-Link Formation as Well as Adduct Structure

Alexander Hegmans, Susan J. Berners‐Price, Murray S. Davies et al. · Journal of the American Chemical Society · 2004 · 106 citations

Kinetic and Equilibria Studies of the Aquation of the Trinuclear Platinum Phase II Anticancer Agent [{<i>trans</i>-PtCl(NH<sub>3</sub>)<sub>2</sub>}<sub>2</sub>{μ-<i>trans</i>-Pt(NH<sub>3</sub>)<sub>2</sub>(NH<sub>2</sub>(CH<sub>2</sub>)<sub>6</sub>NH<sub>2</sub>)<sub>2</sub>}]<sup>4+</sup> (BBR3464)

Murray S. Davies, Donald S. Thomas, Alexander Hegmans et al. · Inorganic Chemistry · 2002 · 71 citations

A comparison of DNA binding profiles of dinuclear platinum compounds with polyamine linkers and the trinuclear platinum phase II clinical agent BBR3464

Tracey D. McGregor, Alexander Hegmans, Jana Kašpárková et al. · JBIC Journal of Biological Inorganic Chemistry · 2002 · 59 citations

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Synthesis and DNA conformational changes of non-covalent polynuclear platinum complexes

Yun Qu, Amanda L. Harris, Alexander Hegmans et al. · Journal of Inorganic Biochemistry · 2004 · 47 citations

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Novel Approaches to Polynuclear Platinum Pro-Drugs. Selective Release of Cytotoxic Platinum−Spermidine Species through Hydrolytic Cleavage of Carbamates

Alexander Hegmans, Yun Qu, Lloyd R. Kèlland et al. · Inorganic Chemistry · 2001 · 39 citations

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