Tracking the Evolution of Non–Small-Cell Lung Cancer

Mariam Jamal‐Hanjani, Gareth A. Wilson, Nicholas McGranahan, +79

New England Journal of Medicine

Phylogenetic ctDNA analysis depicts early-stage lung cancer evolution

Christopher Abbosh, Nicolai J. Birkbak, Gareth A. Wilson, +97

Nature

Allele-Specific HLA Loss and Immune Escape in Lung Cancer Evolution

Nicholas McGranahan, Rachel Rosenthal, Crispin T. Hiley, +218

Cell

Fc-Optimized Anti-CD25 Depletes Tumor-Infiltrating Regulatory T Cells and Synergizes with PD-1 Blockade to Eradicate Established Tumors

Frederick Arce Vargas, Andrew J.S. Furness, Isabelle Solomon, +245

Immunity

Tracking Genomic Cancer Evolution for Precision Medicine: The Lung TRACERx Study

Mariam Jamal‐Hanjani, A. Hackshaw, Yenting Ngai, +67

PLoS Biology

EngineeringPathologyFunctional HeterogeneityTumor BiologyGenomic Cancer Evolution +18

First-line erlotinib in patients with advanced non-small-cell lung cancer unsuitable for chemotherapy (TOPICAL): a double-blind, placebo-controlled, phase 3 trial

Siow Ming Lee, Iftekhar Khan, Sunil Upadhyay, +16

The Lancet Oncology

Randomized Trial of Erlotinib Plus Whole-Brain Radiotherapy for NSCLC Patients With Multiple Brain Metastases

Siow Ming Lee, C. Lewanski, Nicholas Counsell, +7

JNCI Journal of the National Cancer Institute

Multicenter, Phase III, Randomized, Double-Blind, Placebo-Controlled Trial of Pravastatin Added to First-Line Standard Chemotherapy in Small-Cell Lung Cancer (LUNGSTAR)

Michael J. Seckl, Christian H. Ottensmeier, Michael Cullen, +11

Journal of Clinical Oncology

MedicineCancer ManagementPhase IiiPharmacologyClinical Trials +12

The Impact of Cardiac Radiation Dosimetry on Survival After Radiation Therapy for Non-Small Cell Lung Cancer

Sindu Vivekanandan, David Landau, Nicholas Counsell, +9

International Journal of Radiation Oncology*Biology*Physics

A local human Vδ1 T cell population is associated with survival in nonsmall-cell lung cancer

Yin Wu, Dhruva Biswas, Ieva Usaite, +299

Nature Cancer