A novel transferrin receptor-targeted hybrid peptide disintegrates cancer cell membrane to induce rapid killing of cancer cells

Megumi Kawamoto, Tomohisa Horibe, Masayuki Kohno, +1

BMC Cancer

Combination of hybrid peptide with biodegradable gelatin hydrogel for controlled release and enhancement of anti-tumor activity in vivo

Arong Gaowa, Tomohisa Horibe, Masayuki Kohno, +5

Journal of Controlled Release

Biopolymer GelCell-based Drug DeliveryBiodegradable Gelatin HydrogelPolymer-drug ConjugatePeptide Engineering +2

Rapid and large amount of autocrine IL-3 production is responsible for mast cell survival by IgE in the absence of antigen

Masayuki Kohno, Sho Yamasaki, Victor L. J. Tybulewicz, +1

Blood

A novel hybrid peptide targeting EGFR-expressing cancers

Masayuki Kohno, Tomohisa Horibe, Mari Haramoto, +5

European Journal of Cancer

Peptide LibraryEgfr-expressing CancersPeptide TherapeuticMedicineCell Biology +4

Designed hybrid TPR peptide targeting Hsp90 as a novel anticancer agent

Tomohisa Horibe, Masayuki Kohno, Mari Haramoto, +2

Journal of Translational Medicine

The quantity and duration of FcRγ signals determine mast cell degranulation and survival

Sho Yamasaki, Eri Ishikawa, Masayuki Kohno, +1

Blood

P-glycoprotein inhibition by the multidrug resistance-reversing agent MS-209 enhances bioavailability and antitumor efficacy of orally administered paclitaxel

Yoshimitsu Kimura, Jun Aoki, Masayuki Kohno, +3

Cancer Chemotherapy and Pharmacology

OncologyHealth SciencesP-glycoprotein InhibitionMedicineAntitumor Efficacy +7

Melittin, a Metabostatic Peptide Inhibiting Gs Activity

Nobuyuki Fukushima, Masayuki Kohno, Takeshi Kato, +4

Peptides

G Protein-coupled ReceptorMedicineImmunologyGlycobiologyPeptide Therapeutic +3

Oral administration of ferulic acid or ethyl ferulate attenuates retinal damage in sodium iodate-induced retinal degeneration mice

Masayuki Kohno, Kunihiro Musashi, Hanako Ohashi Ikeda, +3

Scientific Reports

Molecular mechanism of cytotoxicity induced by Hsp90-targeted Antp-TPR hybrid peptide in glioblastoma cells

Tomohisa Horibe, Aya Torisawa, Masayuki Kohno, +1

Molecular Cancer