David Ledieu

Potent and Selective Inhibition of Polycythemia by the Quinoxaline JAK2 Inhibitor NVP-BSK805

Fabienne Baffert, Catherine H. Régnier, Alain De Pover et al. · Molecular Cancer Therapeutics · 2010 · 119 citations

Pharmacotherapy, Excellent Selectivity, Pharmaceutical Chemistry +20

Effects of Hepatic Drug-metabolizing Enzyme Induction on Clinical Pathology Parameters in Animals and Man

Daniela Ennulat, Dana B. Walker, F. A. S. Clemo et al. · Toxicologic Pathology · 2010 · 86 citations

Pathology, Fatty Liver Disease, Cholangiopathies +17

Sphingosine 1-Phosphate Produced by Sphingosine Kinase 2 Intrinsically Controls Platelet Aggregation In Vitro and In Vivo

Nicole Urtz, Florian Gaertner, Marie‐Luise von Bruehl et al. · Circulation Research · 2015 · 70 citations

Imatinib does not induce cardiotoxicity at clinically relevant concentrations in preclinical studies

Armin Wolf, Philippe Couttet, Min Dong et al. · Leukemia Research · 2010 · 69 citations

Cardiac Muscle, Cardiomyopathy, Cardiovascular Disease +8

Reduced Activity of Sphingosine-1-Phosphate Lyase Induces Podocyte-related Glomerular Proteinuria, Skin Irritation, and Platelet Activation

Jens Schümann, Armelle Grevot, David Ledieu et al. · Toxicologic Pathology · 2015 · 44 citations

Immunotoxicology, Immunology, Cell Death +19